Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20803450 | 0.83 | L3MBTL1 (0.65) | L3MBTL1SIGMAR1CHRM2HPGDSMN1; SMN2 | |
| SCHEMBL20803498 | 0.77 | HPGD (0.47) | L3MBTL1SIGMAR1CHRM2HPGDSMN1; SMN2 | |
| SCHEMBL22995057 | 0.75 | CHRM2 (0.46) | L3MBTL1SIGMAR1CHRM2SLC5A1 | |
| SCHEMBL20802902 | 0.75 | LTA4H (0.39) | CHRM2CNR1CNR2LTA4HTSHR | |
| SCHEMBL21028857 | 0.74 | MAOA (0.57) | SLC5A1LTA4HTAAR1 | |
| SCHEMBL11767120 | 0.74 | ESR1 (0.52) | CHRM2CNR1CNR2TP53CYP3A4 | |
| SCHEMBL19034502 | 0.74 | SLC5A1 (0.45) | L3MBTL1SIGMAR1CHRM2HPGDSMN1; SMN2 | |
| SCHEMBL21028748 | 0.74 | SLC5A1 (0.43) | L3MBTL1SIGMAR1CHRM2HPGDSMN1; SMN2 | |
| SCHEMBL8095627 | 0.73 | LTA4H (0.53) | CHRM2LTA4HTSHRTAAR1 | |
| SCHEMBL19034462 | 0.70 | POLB (0.49) | HPGDSMN1; SMN2KMT2ASLC5A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489226-B1 | INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1 | LEXICON PHARMACEUTICALS INC (US) | 2021-02-17 | — | — | EP | disclosed |