SCHEMBL2235932

SCHEMBL2235932

Cc1cccc(-n2c3ccc(Br)cc3c3cc(Br)ccc32)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
MAPK1 P28482 3/20 0.48
MAPT P10636 2/20 0.42
HPGD P15428 2/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
ELANE P08246 2/20 0.40
NOTUM Q6P988 1/20 0.40
HSP90AA1 P07900 1/20 0.40
MGLL Q99685 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
RECQL P46063 1/20 0.38
ADRB1 P08588 1/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28619521 0.94 KDM4E (0.46) ALDH1A1MAPK1MAPTHPGDLMNA
SCHEMBL12156924 0.87 MAPT (0.41) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL12879791 0.86 ALDH1A1 (0.48) ALDH1A1MAPK1LMNAMEN1KMT2A
SCHEMBL4546854 0.85 TDP1 (0.45) ALDH1A1HPGDLMNAKDM4EMEN1
SCHEMBL20714996 0.85 MGLL (0.44) ALDH1A1MAPK1MAPTKDM4EMEN1
SCHEMBL5812062 0.85 L3MBTL1 (0.46) ALDH1A1MAPK1HPGDLMNAKDM4E
SCHEMBL31092475 0.84 MAPT (0.39) ALDH1A1MAPK1MAPTHPGDLMNA
SCHEMBL12362760 0.84 DCTPP1 (0.40) ALDH1A1MAPK1MAPTHPGDLMNA
SCHEMBL15025952 0.83 DNM1 (0.37) ALDH1A1MAPK1MAPTHPGDLMNA
SCHEMBL4251581 0.82 DNM1 (0.39) ALDH1A1MAPK1MAPTHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9085537-B2 Photoelectric element and imaging device and driving methods therefor FUJIFILM CORPORATION (JP) 2015-07-21 US disclosed
US-20120298846-A1 PHOTOELECTRIC ELEMENT AND IMAGING DEVICE AND DRIVING METHODS THEREFOR FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
WO-2011099606-A1 PHOTOELECTRIC ELEMENT AND IMAGING DEVICE AND DRIVING METHODS THEREFOR FUJIFILM CORPORATION (JP) 2011-08-18 WO disclosed