Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PMM2 | O15305 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032411 | 0.88 | HTR6 (0.46) | MAPTKDM4EMAPK1L3MBTL1PTGDR2 | |
| SCHEMBL21031946 | 0.85 | PTGDR2 (0.53) | PTGDR2CYP2C9PTGDRPTGS1SLC6A4 | |
| SCHEMBL24179951 | 0.80 | PTGDR2 (0.56) | PTGDR2CYP2C9PTGDR | |
| SCHEMBL21032472 | 0.80 | PTGDR2 (0.48) | MAPTTP53PTGDR2PTGS1 | |
| SCHEMBL21032707 | 0.78 | MAPK14 (0.43) | MAPTKDM4EMAPK1L3MBTL1PTGDR2 | |
| SCHEMBL21032706 | 0.76 | PTGDR2 (0.36) | MAPTKDM4EMAPK1L3MBTL1PTGDR2 | |
| SCHEMBL20631884 | 0.76 | KDM4E (0.50) | MAPTKDM4EMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL21032166 | 0.75 | PTGDR2 (0.59) | PTGDR2CYP2C9PTGDRPTGS1 | |
| SCHEMBL21032557 | 0.74 | PTGDR2 (0.54) | PTGDR2CYP2C9PTGDR | |
| SCHEMBL24180036 | 0.73 | PTGDR2 (0.63) | PTGDR2CYP2C9PTGS1SLC6A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489233-A1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |