Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21679591 | 0.95 | CA12 (0.45) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL21034809 | 0.95 | CA12 (0.45) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL21034803 | 0.90 | CA12 (0.41) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL21679592 | 0.87 | CA12 (0.39) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL13871217 | 0.86 | POLB (0.41) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL13722220 | 0.83 | POLB (0.49) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL21033752 | 0.83 | THRB (0.49) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL13431250 | 0.83 | MAPT (0.41) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL13431253 | 0.83 | MAPT (0.40) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL838367 | 0.81 | MAPT (0.44) | NPC1RAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159680-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION WITH IMPROVED STRENGTH IN AQUEOUS ENVIRONMENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2023-05-25 | — | — | US | disclosed |
| US-11584817-B2 | Orthodontic articles comprising cured free-radically polymerizable composition with improved strength in aqueous environment | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20210386522-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION COMPRISING POLYMER OR MACROMOLECULE WITH PHOTOINITIATOR GROUP | 3M INNOVATIVE PROPERTIES COMPANY | 2021-12-16 | — | — | US | disclosed |
| US-20210238328-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION WITH IMPROVED STRENGTH IN AQUEOUS ENVIRONMENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2021-08-05 | — | — | US | disclosed |
| US-20210186820-A1 | ORTHODONTIC ARTICLES COMPRISING POLYMERIZED COMPOSITION COMPRISING AT LEAST TWO FREE-RADICAL INITIATORS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2021-06-24 | — | — | US | disclosed |
| US-20200048392-A1 | PHYSICALLY CROSSLINKABLE (METH)ACRYLATE COPOLYMER COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY | 2020-02-13 | — | — | US | disclosed |
| WO-2019104079-A1 | ORTHODONTIC ARTICLES COMPRISING POLYMERIZED COMPOSITION COMPRISING AT LEAST TWO FREE-RADICAL INITIATORS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104072-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION COMPRISING POLYMER OR MACROMOLECULE WITH PHOTOINITIATOR GROUP | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210186820-A1 | ORTHODONTIC ARTICLES COMPRISING POLYMERIZED COMPOSITION COMPRISING AT LEAST TWO FREE-RADICAL INITIATORS | AASDHPPT, ELL, APEH | CA12 4243/4885CA1 2326/4885CA2 1546/4885 |
| US-20230159680-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION WITH IMPROVED STRENGTH IN AQUEOUS ENVIRONMENT | ELL, PCNA, PAM | CA12 4609/4885CA1 3370/4885CA2 3304/4885 |
| US-20210238328-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION WITH IMPROVED STRENGTH IN AQUEOUS ENVIRONMENT | ELL, PCNA, PAM | CA12 4609/4885CA1 3370/4885CA2 3304/4885 |
| US-11584817-B2 | Orthodontic articles comprising cured free-radically polymerizable composition with improved strength in aqueous environment | ELL, PCNA, PAM | CA12 4609/4885CA1 3370/4885CA2 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.