Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151307 | 0.89 | THRB (0.60) | THRBTSHRHSD17B10MAPTL3MBTL1 | |
| SCHEMBL26373331 | 0.89 | THRB (0.47) | THRBNPC1USP2ALOX15TSHR | |
| SCHEMBL23422530 | 0.86 | THRB (0.56) | THRBNPC1USP2ALOX15TSHR | |
| SCHEMBL12866520 | 0.85 | THRB (0.52) | THRBNPC1MAPTCA12CA1 | |
| SCHEMBL13722220 | 0.84 | POLB (0.49) | NPC1USP2ALOX15TSHRMAPK1 | |
| SCHEMBL13707208 | 0.84 | THRB (0.53) | THRBTSHRHSD17B10MAPTL3MBTL1 | |
| SCHEMBL21034810 | 0.83 | CA12 (0.48) | NPC1MAPTCA12CA1CA2 | |
| SCHEMBL23450561 | 0.83 | THRB (0.56) | THRBNPC1MAPK1HSD17B10MAPT | |
| SCHEMBL25719876 | 0.83 | THRB (0.47) | THRBMAPK1MAPTCA12CA1 | |
| SCHEMBL13431250 | 0.82 | MAPT (0.41) | NPC1USP2ALOX15TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11759298-B2 | Photopolymerizable compositions including a urethane component and a monofunctional reactive diluent, articles, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-09-19 | — | — | US | disclosed |
| US-11759298-B2 | Photopolymerizable compositions including a urethane component and a monofunctional reactive diluent, articles, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-09-19 | — | — | US | disclosed |
| US-20230159680-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION WITH IMPROVED STRENGTH IN AQUEOUS ENVIRONMENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2023-05-25 | — | — | US | disclosed |
| US-20230159680-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION WITH IMPROVED STRENGTH IN AQUEOUS ENVIRONMENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2023-05-25 | — | — | US | disclosed |
| US-20230129152-A1 | Compounds Comprising Perfluorinated Group, Photoinitiator Group, and Amide Linking Group | 3M INNOVATIVE PROPERTIES COMPANY | 2023-04-27 | — | — | US | disclosed |
| US-20230129152-A1 | Compounds Comprising Perfluorinated Group, Photoinitiator Group, and Amide Linking Group | 3M INNOVATIVE PROPERTIES COMPANY | 2023-04-27 | — | — | US | disclosed |
| US-11584817-B2 | Orthodontic articles comprising cured free-radically polymerizable composition with improved strength in aqueous environment | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20210386522-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION COMPRISING POLYMER OR MACROMOLECULE WITH PHOTOINITIATOR GROUP | 3M INNOVATIVE PROPERTIES COMPANY | 2021-12-16 | — | — | US | disclosed |
| WO-2021229331-A1 | COMPOUNDS COMPRISING PERFLUORINATED GROUP, PHOTOINITIATOR GROUP, AND AMIDE LINKING GROUP | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-11-18 | — | — | WO | disclosed |
| WO-2021229547-A1 | MULTILAYER OPTICAL FILMS COMPRISING AT LEAST ONE FLUORINATED (CO)POLYMER LAYER MADE USING A FLUORINATED PHOTOINITIATOR, AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-11-18 | — | — | WO | disclosed |
| US-20210238328-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION WITH IMPROVED STRENGTH IN AQUEOUS ENVIRONMENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2021-08-05 | — | — | US | disclosed |
| US-20210186820-A1 | ORTHODONTIC ARTICLES COMPRISING POLYMERIZED COMPOSITION COMPRISING AT LEAST TWO FREE-RADICAL INITIATORS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2021-06-24 | — | — | US | disclosed |
| US-20200362157-A1 | PHOTOPOLYMERIZABLE COMPOSITIONS INCLUDING A URETHANE COMPONENT AND A MONOFUNCTIONAL REACTIVE DILUENT, ARTICLES, AND METHODS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2020-11-19 | — | — | US | disclosed |
| US-20200332046-A1 | PHOTOPOLYMERIZABLE COMPOSITIONS INCLUDING A POLYPROPYLENE OXIDE COMPONENT, ARTICLES, AND METHODS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2020-10-22 | — | — | US | disclosed |
| WO-2019104079-A1 | ORTHODONTIC ARTICLES COMPRISING POLYMERIZED COMPOSITION COMPRISING AT LEAST TWO FREE-RADICAL INITIATORS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019103855-A1 | PHOTOPOLYMERIZABLE COMPOSITIONS INCLUDING A URETHANE COMPONENT AND A MONOFUNCTIONAL REACTIVE DILUENT, ARTICLES, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104072-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION COMPRISING POLYMER OR MACROMOLECULE WITH PHOTOINITIATOR GROUP | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210186820-A1 | ORTHODONTIC ARTICLES COMPRISING POLYMERIZED COMPOSITION COMPRISING AT LEAST TWO FREE-RADICAL INITIATORS | AASDHPPT, ELL, APEH | THRB 4266/4885NPC1 4751/4885USP2 3586/4885 |
| US-20230129152-A1 | Compounds Comprising Perfluorinated Group, Photoinitiator Group, and Amide Linking Group | PFAS, AFF4, AFF1 | THRB 1513/4885NPC1 3463/4885USP2 2247/4885 |
| US-20200332046-A1 | PHOTOPOLYMERIZABLE COMPOSITIONS INCLUDING A POLYPROPYLENE OXIDE COMPONENT, ARTICLES, AND METHODS | HTR3D, UROD, PPOX | THRB 3972/4885NPC1 4855/4885USP2 609/4885 |
| US-20200362157-A1 | PHOTOPOLYMERIZABLE COMPOSITIONS INCLUDING A URETHANE COMPONENT AND A MONOFUNCTIONAL REACTIVE DILUENT, ARTICLES, AND METHODS | HTR3D, UROD, UGT1A3 | THRB 4293/4885NPC1 4803/4885USP2 246/4885 |
| US-20230159680-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION WITH IMPROVED STRENGTH IN AQUEOUS ENVIRONMENT | ELL, PCNA, PAM | THRB 4328/4885NPC1 4783/4885USP2 620/4885 |
| US-20210238328-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION WITH IMPROVED STRENGTH IN AQUEOUS ENVIRONMENT | ELL, PCNA, PAM | THRB 4328/4885NPC1 4783/4885USP2 620/4885 |
| US-11584817-B2 | Orthodontic articles comprising cured free-radically polymerizable composition with improved strength in aqueous environment | ELL, PCNA, PAM | THRB 4328/4885NPC1 4783/4885USP2 620/4885 |
| US-11759298-B2 | Photopolymerizable compositions including a urethane component and a monofunctional reactive diluent, articles, and methods | HTR3D, UROD, UGT1A3 | THRB 4293/4885NPC1 4803/4885USP2 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.