Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.59 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193876 | 0.89 | ALDH1A1 (0.48) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL6878804 | 0.89 | ALOX5 (0.57) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL7077598 | 0.89 | ALDH1A1 (0.48) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL6881273 | 0.84 | ALDH1A1 (0.43) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL15889361 | 0.82 | PIM1 (0.44) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL25065125 | 0.80 | NOTUM (0.47) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL12733344 | 0.80 | KIF11 (0.46) | ALDH1A1MAPTTDP1TSHRAPP | |
| SCHEMBL1176397 | 0.80 | ALDH1A1 (0.67) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL180815 | 0.80 | ALDH1A1 (0.59) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL31146788 | 0.80 | ALDH1A1 (0.67) | ALDH1A1ALOX15SMN1; SMN2CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200375949-A1 | BISPHENOL COMPOUNDS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-12-03 | — | — | US | disclosed |
| US-20200375949-A1 | BISPHENOL COMPOUNDS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-12-03 | — | — | US | disclosed |
| WO-2019104153-A1 | BISPHENOL COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2019-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200375949-A1 | BISPHENOL COMPOUNDS | RPP30, RPS10, RPS20 | ALDH1A1 1053/4885ALOX15 2231/4885SMN1; SMN2 4506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.