Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.48 |
| ▸ | HNF4A | P41235 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035191 | 0.89 | ALDH1A1 (0.59) | ALOX5ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL3565632 | 0.84 | ALOX5 (0.57) | ALOX5ALDH1A1TSHRTDP1ACMSD | |
| SCHEMBL5193876 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1KDM4EMAPT | |
| SCHEMBL27991629 | 0.81 | RXRA (0.42) | ALOX5ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL28521094 | 0.81 | RARB (0.54) | ALOX5ALDH1A1TSHRTDP1ACMSD | |
| SCHEMBL7077598 | 0.80 | ALDH1A1 (0.48) | ALOX5ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL6881273 | 0.79 | ALDH1A1 (0.43) | ALOX5ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL12733344 | 0.79 | KIF11 (0.46) | ALDH1A1TSHRTDP1MAPTAPP | |
| SCHEMBL2291021 | 0.78 | CA2 (0.48) | ALOX5ALDH1A1TSHRTDP1ACMSD | |
| SCHEMBL13840641 | 0.78 | CA2 (0.71) | ALOX5ALDH1A1TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852486-A2 | ANTIPLAQUE ORAL COMPOSITION | Colgate-Palmolive Company (US) | 1998-07-15 | — | — | EP | claimed |
| US-5723500-A | WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES | COLGATE-PALMOLIVE COMPANY (US) | 1998-03-03 | — | — | US | claimed |
| WO-1997010800-A2 | ANTIPLAQUE ORAL COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 1997-03-27 | — | — | WO | claimed |
| US-7932283-B2 | Fungicide N-cyclopropyl-sulfonylamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| US-7932283-B2 | Fungicide N-cyclopropyl-sulfonylamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
| US-6753451-B2 | REACTING KETO COMPOUND, 1,3-DIOXOLANE, AND AN AMMONIUM HALIDE TO YIELD A B-AMINOKETONE; REACTING WITH N-ACETYLMETHYLPYRIDINIUM HALIDE; FRIEDEL-CRAFTS ALKYLATION | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-06-22 | — | — | US | disclosed |
| US-20030191349-A1 | Process for the preparation of phenylphenol compounds | CIBA SPECIALTY CHEMICALS CORP. | 2003-10-09 | — | — | US | disclosed |
| EP-1313689-A1 | PROCESS FOR THE PREPARATION OF PHENYLPHENOL COMPOUNDS | Ciba SC Holding AG (CH) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018311-A1 | PROCESS FOR THE PREPARATION OF PHENYLPHENOL COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-03-07 | — | — | WO | disclosed |
| EP-0852486-A2 | ANTIPLAQUE ORAL COMPOSITION | Colgate-Palmolive Company (US) | 1998-07-15 | — | — | EP | disclosed |
| US-5723500-A | WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES | COLGATE-PALMOLIVE COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| WO-1997010800-A2 | ANTIPLAQUE ORAL COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 1997-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191349-A1 | Process for the preparation of phenylphenol compounds | PAH, CYP1A1, CYP2D6 | ALOX5 1004/4885ALDH1A1 212/4885TSHR 1327/4885 |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | CYP51A1, ERG28, CBR3 | ALOX5 3048/4885ALDH1A1 2140/4885TSHR 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.