SCHEMBL5193876

SCHEMBL5193876

CC(C)(C)c1ccc(-c2ccc(C(C)(C)C)c(O)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
ALOX15 P16050 3/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 2/20 0.48
CYP1A2 P05177 1/20 0.48
ATP2A2 P16615 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ATP2A3 Q93084 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
HSD17B10 Q99714 2/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 2/20 0.46
TYR P14679 2/20 0.46
KIF11 P52732 4/20 0.45
TSHR P16473 2/20 0.43
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21035191 0.89 ALDH1A1 (0.59) ALDH1A1ALOX15MAPTKDM4ECYP1A2
SCHEMBL6878804 0.84 ALOX5 (0.57) ALDH1A1ALOX15MAPTKDM4ECYP1A2
SCHEMBL8707369 0.84 ALDH1A1 (0.55) ALDH1A1ALOX15MAPTKDM4ECYP1A2
SCHEMBL20713860 0.83 ALDH1A1 (0.68) ALDH1A1ALOX15MAPTTDP1HSD17B10
SCHEMBL142987 0.83 ALDH1A1 (0.67) ALDH1A1ALOX15MAPTKDM4ECYP1A2
Thymol SCHEMBL28270041 0.82 TRPA1 (0.57) ALDH1A1MAPTLMNATSHRHSD17B2
SCHEMBL29511701 0.81 ALDH1A1 (0.64) ALDH1A1ALOX15MAPTKDM4ECYP1A2
SCHEMBL28698158 0.81 ALDH1A1 (0.64) ALDH1A1ALOX15MAPTKDM4ECYP1A2
SCHEMBL7077598 0.80 ALDH1A1 (0.48) ALDH1A1ALOX15MAPTKDM4ECYP1A2
SCHEMBL6881273 0.79 ALDH1A1 (0.43) ALDH1A1ALOX15MAPTKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1303263-A2 ANTIBACTERIAL METHOD AND COMPOSITION WTH PHENOLIC COMPOUNDS Colgate-Palmolive Company (US) 2003-04-23 EP claimed
US-6403652-B1 A METHOD FOR INHIBITING METHICILLIN DRUG RESISTANT BACTERIA USING A PHENOLIC COMPOUND. COLGATE-PALMOLIVE COMPANY 2002-06-11 US claimed
WO-2002002098-A2 ANTIBACTERIAL METHOD AND COMPOSITION WITH PHENOLIC COMPOUNDS COLGATE-PALMOLIVE COMPANY (US) 2002-01-10 WO claimed
EP-0852486-A2 ANTIPLAQUE ORAL COMPOSITION Colgate-Palmolive Company (US) 1998-07-15 EP claimed
US-5723500-A WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES COLGATE-PALMOLIVE COMPANY (US) 1998-03-03 US claimed
WO-1997010800-A2 ANTIPLAQUE ORAL COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 1997-03-27 WO claimed
EP-3769624-B1 ENHANCING THE ANTIMICROBIAL ACTIVITY OF BIOCIDES WITH POLYMERS BASF SE (DE) 2024-10-30 EP disclosed
US-11666050-B2 Enhancing the antimicrobial activity of biocides with polymers BASF SE (DE) 2023-06-06 US disclosed
US-11647746-B2 Enhancing the antimicrobial activity of biocides with polymers BASF SE (DE) 2023-05-16 US disclosed
CN-109054378-B Enhancing antimicrobial activity of biocides with polymers 巴斯夫欧洲公司 2021-10-01 CN disclosed
EP-3769624-A2 ENHANCING THE ANTIMICROBIAL ACTIVITY OF BIOCIDES WITH POLYMERS BASF SE (DE) 2021-01-27 EP disclosed
EP-2817353-B1 ENHANCING THE ANTIMICROBIAL ACTIVITY OF BIOCIDES WITH POLYMERS BASF SE (DE) 2021-01-13 EP disclosed
US-20200221694-A1 Enhancing the Antimicrobial Activity of Biocides with Polymers BASF SE (DE) 2020-07-16 US disclosed
US-6403652-B1 A METHOD FOR INHIBITING METHICILLIN DRUG RESISTANT BACTERIA USING A PHENOLIC COMPOUND. COLGATE-PALMOLIVE COMPANY 2002-06-11 US disclosed
WO-2002018311-A1 PROCESS FOR THE PREPARATION OF PHENYLPHENOL COMPOUNDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-03-07 WO disclosed
WO-2002002098-A2 ANTIBACTERIAL METHOD AND COMPOSITION WITH PHENOLIC COMPOUNDS COLGATE-PALMOLIVE COMPANY (US) 2002-01-10 WO disclosed
WO-2001062082-A2 USE OF PHENYLETHYLAMINE DERIVATIVES FOR THE ANITMICROBIAL TREATMENT OF SURFACES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-30 WO disclosed
EP-0852486-A2 ANTIPLAQUE ORAL COMPOSITION Colgate-Palmolive Company (US) 1998-07-15 EP disclosed
US-5723500-A WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES COLGATE-PALMOLIVE COMPANY (US) 1998-03-03 US disclosed
WO-1997010800-A2 ANTIPLAQUE ORAL COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 1997-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11647746-B2 Enhancing the antimicrobial activity of biocides with polymers CAT, AOC1, DDT ALDH1A1 787/4885ALOX15 1578/4885MAPT 4500/4885
US-11666050-B2 Enhancing the antimicrobial activity of biocides with polymers CAT, AOC1, DDT ALDH1A1 787/4885ALOX15 1578/4885MAPT 4500/4885
US-20200221694-A1 Enhancing the Antimicrobial Activity of Biocides with Polymers CAT, AOC1, DDT ALDH1A1 787/4885ALOX15 1578/4885MAPT 4500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.