Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP13 | P45452 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035379 | 0.91 | MMP1 (0.49) | SIGMAR1MMP1MMP13MMP9MMP3 | |
| SCHEMBL21034943 | 0.88 | GHSR (0.47) | SIGMAR1MMP1MMP13MMP9MMP3 | |
| SCHEMBL21035381 | 0.85 | GHSR (0.41) | SIGMAR1MMP1MMP13MMP9MMP3 | |
| SCHEMBL21036206 | 0.83 | MEN1 (0.45) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21035327 | 0.83 | MEN1 (0.45) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21034954 | 0.83 | MEN1 (0.45) | MMP1MMP13MMP9MMP3MMP7 | |
| Trifluoroacetic Acid SCHEMBL21002066 | 0.83 | GHSR (0.39) | SIGMAR1MMP1MMP13MMP9MMP3 | |
| SCHEMBL21035342 | 0.81 | GHSR (0.47) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21035443 | 0.81 | GHSR (0.47) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21035574 | 0.80 | MMP13 (0.53) | MMP1MMP13MMP9MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |