Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 9/20 | 0.53 |
| ▸ | MMP1 | P03956 | 8/20 | 0.53 |
| ▸ | MMP3 | P08254 | 7/20 | 0.53 |
| ▸ | MMP7 | P09237 | 6/20 | 0.53 |
| ▸ | MMP9 | P14780 | 5/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035359 | 0.82 | MMP1 (0.52) | MMP13MMP1MMP3MMP7MMP9 | |
| SCHEMBL6506359 | 0.81 | MMP13 (0.71) | MMP13MMP1MMP9ADAM17 | |
| SCHEMBL21035378 | 0.80 | SIGMAR1 (0.48) | MMP13MMP1MMP3MMP7MMP9 | |
| SCHEMBL21035632 | 0.80 | CHRM2 (0.43) | MMP1MMP3ADAM17ALDH1A1HTT | |
| SCHEMBL21035634 | 0.80 | CHRM2 (0.43) | MMP1MMP3ADAM17ALDH1A1HTT | |
| SCHEMBL21035326 | 0.79 | MMP1 (0.42) | MMP1ADAM17ALDH1A1HTTKMT2A | |
| SCHEMBL6283507 | 0.78 | MMP1 (0.60) | MMP13MMP1MMP3MMP7MMP9 | |
| SCHEMBL21035511 | 0.77 | MMP1 (0.47) | MMP13MMP1ADAM17ALDH1A1HTT | |
| SCHEMBL6498571 | 0.77 | MMP1 (0.55) | MMP13MMP1MMP3MMP7MMP9 | |
| SCHEMBL21035416 | 0.76 | ADAM17 (0.55) | MMP13MMP1MMP3MMP7ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |