Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935780 | 0.84 | PPARA (0.52) | SMN1; SMN2PPARAPPARGPTGDR2MAPT | |
| SCHEMBL8935782 | 0.84 | PPARA (0.52) | SMN1; SMN2PPARAPPARGPTGDR2MAPT | |
| SCHEMBL2885186 | 0.83 | PTGDR2 (0.57) | SMN1; SMN2LTB4RPPARAALDH1A1PTGDR2 | |
| SCHEMBL7568990 | 0.82 | LMNA (0.49) | SMN1; SMN2LTB4RPPARAALDH1A1PPARG | |
| SCHEMBL8935737 | 0.82 | LMNA (0.49) | SMN1; SMN2LTB4RPPARAALDH1A1PPARG | |
| SCHEMBL2103556 | 0.81 | PKM (0.54) | SMN1; SMN2PPARAPPARGPTGDR2MAPT | |
| SCHEMBL11364459 | 0.81 | PPARA (0.50) | SMN1; SMN2PPARAALDH1A1PPARGPTGDR2 | |
| SCHEMBL5861916 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2LTB4RPPARAPPARGPTGDR2 | |
| SCHEMBL22646881 | 0.79 | HTT (0.44) | SMN1; SMN2ALDH1A1HTTMAPTPKM | |
| SCHEMBL30688864 | 0.79 | HTT (0.44) | SMN1; SMN2ALDH1A1HTTMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737425-B1 | SUCH AS 1-((4-CYANO-5-METHYL-4-PHENYL)HEXYL)-4-(2-(4-FLUORO -PHENOXY)ETHYL)PIPERAZINE; NERVE SELECTIVE CALCIUM ANTAGONISTS | EISAI CO., LTD. (JP) | 2004-05-18 | — | — | US | disclosed |