Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.40 |
| ▸ | MMP1 | P03956 | 5/20 | 0.40 |
| ▸ | MMP13 | P45452 | 5/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AOC2 | O75106 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035485 | 1.00 | GHSR (0.40) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035621 | 0.96 | GHSR (0.44) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035568 | 0.90 | MMP1 (0.43) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035569 | 0.90 | MMP1 (0.43) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035360 | 0.90 | MMP1 (0.38) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21035506 | 0.88 | GHSR (0.44) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035605 | 0.88 | GHSR (0.44) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035486 | 0.87 | MMP13 (0.39) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21034943 | 0.87 | GHSR (0.47) | GHSRMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035342 | 0.86 | GHSR (0.47) | GHSRMMP1MMP13MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |