Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.33 |
| ▸ | HPGD | P15428 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815176 | 0.85 | TYR (0.42) | KDM4EALDH1A1GAAHSD17B10TSHR | |
| SCHEMBL2814697 | 0.85 | TYR (0.42) | KDM4EALDH1A1GAAHSD17B10TSHR | |
| SCHEMBL2813389 | 0.85 | TYR (0.42) | KDM4EALDH1A1GAAHSD17B10TSHR | |
| SCHEMBL4585477 | 0.83 | TYR (0.41) | KDM4EALDH1A1GAAHSD17B10TSHR | |
| SCHEMBL30320265 | 0.83 | GABRA1 (0.39) | HSD17B3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14281968 | 0.83 | GABRA1 (0.39) | HSD17B3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2812711 | 0.77 | MAPT (0.36) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL17768931 | 0.77 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL26707584 | 0.74 | HMGCR (0.37) | HSD17B3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16632779 | 0.73 | GABRA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240074305-A1 | TETRAHYDRONAPHTHALENE-BASED ORGANIC COMPOUND, MIXTURE, COMPOSITION, AND ORGANIC ELECTRONIC DEVICE | SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) | 2024-02-29 | — | — | US | disclosed |
| US-11639339-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-05-02 | — | — | US | disclosed |
| US-11639339-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-05-02 | — | — | US | disclosed |
| WO-2019101835-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639339-B2 | Materials for organic electroluminescent devices | L1CAM, EFNA1, EPCAM | HSD17B3 2087/4885KDM4E 3061/4885ALDH1A1 33/4885 |
| US-20240074305-A1 | TETRAHYDRONAPHTHALENE-BASED ORGANIC COMPOUND, MIXTURE, COMPOSITION, AND ORGANIC ELECTRONIC DEVICE | EXOC1, TRPA1, CYBA | HSD17B3 724/4885KDM4E 3484/4885ALDH1A1 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.