SCHEMBL16632779

SCHEMBL16632779

CC(C)Cc1cc(Br)c2ccc3c(CC(C)C)cc(Br)c4ccc1c2c43

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
TBXA2R P21731 1/20 0.32
PTGER1 P34995 1/20 0.32
PTGER3 P43115 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30320265 0.77 GABRA1 (0.39) GABRA1GABRB2TBXA2R
SCHEMBL14281968 0.77 GABRA1 (0.39) GABRA1GABRB2TBXA2R
SCHEMBL21037083 0.73 HSD17B3 (0.40)
SCHEMBL11924888 0.73 LMNA (0.38)
SCHEMBL28789783 0.73 PDE4D (0.32)
SCHEMBL24807660 0.71 CTSB (0.42) GABRA1GABRB2
SCHEMBL1005904 0.69 HSP90AA1 (0.33)
SCHEMBL697982 0.68 GABRA1 (0.37) GABRA1GABRB2
SCHEMBL16632693 0.68 GABRA1 (0.40) GABRA1GABRB2
SCHEMBL2815176 0.68 TYR (0.42) ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790142-B Deuterated aromatic amine derivative and preparation method and application thereof 广州华睿光电材料有限公司 2021-09-10 CN disclosed
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed