Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154227 | 0.83 | TDP1 (0.50) | ADORA3ALDH1A1KMT2ATDP1SLC6A2 | |
| SCHEMBL21037483 | 0.82 | ALDH1A1 (0.52) | ADORA3ALDH1A1KMT2ATDP1SLC6A2 | |
| SCHEMBL22342960 | 0.81 | ADORA3 (0.46) | ADORA3ALDH1A1KMT2ATDP1SLC6A2 | |
| SCHEMBL21037180 | 0.79 | ADORA3 (0.46) | ADORA3ALDH1A1KMT2ATDP1SLC6A2 | |
| SCHEMBL29067630 | 0.77 | ADORA3 (0.45) | ADORA3ALDH1A1KMT2ATDP1SLC6A2 | |
| SCHEMBL14768871 | 0.75 | TDP1 (0.66) | ADORA3ALDH1A1KMT2ATDP1SLC6A2 | |
| SCHEMBL22005651 | 0.72 | ALDH1A1 (0.53) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL17132103 | 0.72 | TDP1 (0.50) | ADORA3ALDH1A1KMT2ATDP1SLC6A2 | |
| SCHEMBL22005653 | 0.72 | JMJD6 (0.52) | ADORA3ALDH1A1KMT2ATDP1SLC6A2 | |
| SCHEMBL20154213 | 0.72 | ADORA3 (0.47) | ADORA3ALDH1A1KMT2ATDP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386973-B1 | PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-12 | — | — | EP | disclosed |
| US-20190161499-A1 | PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190161499-A1 | PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES | ACHE, AADAC, ATL3 | ADORA3 339/4885ALDH1A1 533/4885KMT2A 1718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.