Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21042217 | 0.97 | FKBP1A (0.42) | CNR1CNR2FKBP1AKCNK3 | |
| SCHEMBL29593544 | 0.88 | FKBP1A (0.45) | CNR1CNR2FKBP1ASPHK1SPHK2 | |
| SCHEMBL19506075 | 0.88 | FKBP1A (0.45) | CNR1CNR2FKBP1ASPHK1SPHK2 | |
| SCHEMBL19505773 | 0.86 | FKBP1A (0.48) | FKBP1ASPHK1SPHK2 | |
| SCHEMBL21041363 | 0.85 | PIK3CD (0.39) | ALDH1A1 | |
| SCHEMBL21042058 | 0.81 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL21041369 | 0.81 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL21042231 | 0.81 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL21042060 | 0.80 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL19505980 | 0.75 | FKBP1A (0.41) | CNR1CNR2FKBP1ASPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647671-B2 | Promysalin analogues and methods of use thereof | Temple University—Of the Commonwealth System of Higher Education (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190161444-A1 | Novel Promysalin Analogues and Methods of Use Thereof | Temple University--of the Commonwealth System of Higher Education | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647671-B2 | Promysalin analogues and methods of use thereof | CCL11, MAN2A1, PREP | CNR1 1289/4885CNR2 1183/4885FKBP1A 1819/4885 |
| US-20190161444-A1 | Novel Promysalin Analogues and Methods of Use Thereof | MASP2, MAN2A1, CCL11 | CNR1 1776/4885CNR2 1844/4885FKBP1A 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.