Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043867 | 0.92 | POLB (0.59) | POLBLMNAUSP2CYP19A1TP53 | |
| SCHEMBL21043802 | 0.90 | MAPT (0.53) | POLBLMNACYP19A1ATAD2TP53 | |
| SCHEMBL21043825 | 0.89 | CYP19A1 (0.54) | POLBLMNACYP19A1ATAD2TP53 | |
| SCHEMBL21043884 | 0.89 | CYP19A1 (0.50) | POLBLMNACYP19A1ATAD2TP53 | |
| SCHEMBL21043862 | 0.89 | LMNA (0.52) | POLBLMNAATAD2TP53MAPT | |
| SCHEMBL21043885 | 0.87 | CYP19A1 (0.54) | POLBLMNAUSP2CYP19A1ATAD2 | |
| SCHEMBL21043848 | 0.86 | POLB (0.46) | POLBLMNAATAD2MAPT | |
| SCHEMBL21043832 | 0.83 | POLB (0.48) | POLBLMNAATAD2TP53MAPT | |
| SCHEMBL21043831 | 0.83 | ATAD2 (0.46) | POLBLMNAATAD2TP53MAPT | |
| SCHEMBL21043855 | 0.82 | MAPT (0.52) | POLBLMNACYP19A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |