Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043844 | 0.92 | THRB (0.43) | THRBPOLBLMNATP53MAPT | |
| SCHEMBL21043862 | 0.85 | LMNA (0.52) | ATAD2THRBPOLBLMNATP53 | |
| SCHEMBL21043802 | 0.84 | MAPT (0.53) | ATAD2THRBPOLBLMNATP53 | |
| SCHEMBL21043884 | 0.83 | CYP19A1 (0.50) | ATAD2POLBLMNATP53MAPT | |
| SCHEMBL21043790 | 0.83 | POLB (0.61) | ATAD2POLBLMNATP53MAPT | |
| SCHEMBL21043825 | 0.81 | CYP19A1 (0.54) | ATAD2POLBLMNATP53MAPT | |
| SCHEMBL21043885 | 0.81 | CYP19A1 (0.54) | ATAD2THRBPOLBLMNAMAPT | |
| SCHEMBL19865911 | 0.80 | ATAD2 (0.54) | ATAD2POLBLMNATP53MAPT | |
| SCHEMBL21043845 | 0.79 | BRD4 (0.53) | ATAD2POLBLMNATP53MAPT | |
| SCHEMBL21043854 | 0.78 | POLB (0.50) | ATAD2POLBLMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |