SCHEMBL21049529

SCHEMBL21049529

CCCN(c1ccccc1)C(CC)CC[Si](OC)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 16/20 0.35
SIGMAR1 Q99720 1/20 0.34
TRPM8 Q7Z2W7 1/20 0.33
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16756619 0.82 ALDH1A1 (0.33) SIGMAR1
SCHEMBL20150135 0.79 TP53 (0.39) SIGMAR1TAAR1
SCHEMBL20133786 0.77 NPC1 (0.38) CRHR1SIGMAR1
SCHEMBL8436010 0.72 TDP1 (0.38) CRHR1SIGMAR1
SCHEMBL8438797 0.71 TAAR1 (0.35) TAAR1
SCHEMBL11328811 0.70 TP53 (0.41) TRPM8TAAR1
SCHEMBL2763678 0.68 MTNR1A (0.46) SIGMAR1
SCHEMBL3956329 0.68 TAAR1 (0.39) CRHR1SIGMAR1TAAR1
SCHEMBL25684761 0.68 TAAR1 (0.39) CRHR1SIGMAR1TAAR1
SCHEMBL8959902 0.67 TAAR1 (0.49) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3505557-B1 RUBBER CROSSLINKED PRODUCT ZEON CORP (JP) 2024-05-01 EP disclosed
EP-3495394-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING POLYMER COMPOSITION SUMITOMO CHEMICAL CO (JP) 2023-04-12 EP disclosed
CN-109563186-B Method for producing modified conjugated diene polymer and method for producing polymer composition 住友化学株式会社 2022-04-15 CN disclosed
CN-109563276-B Crosslinked rubber 日本瑞翁株式会社 2021-12-07 CN disclosed
US-11046791-B2 Method for producing modified conjugated diene polymer and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-29 US disclosed
US-10968335-B2 Rubber crosslinked product ZEON CORPORATION (JP) 2021-04-06 US disclosed
US-20200216578-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-07-09 US disclosed
US-20190330454-A1 RUBBER CROSSLINKED PRODUCT ZEON CORPORATION (JP) 2019-10-31 US disclosed
WO-2019163772-A1 CROSSLINKED RUBBER 日本ゼオン株式会社 2019-08-29 WO disclosed
WO-2019163773-A1 CROSSLINKED RUBBER 日本ゼオン株式会社 2019-08-29 WO disclosed
EP-3505557-A1 RUBBER CROSSLINKED PRODUCT Zeon Corporation (JP) 2019-07-03 EP disclosed
EP-3495394-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING POLYMER COMPOSITION Sumitomo Chemical Company, Limited (JP) 2019-06-12 EP disclosed