Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21055989 | 1.00 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPK1CYP3A4CYP2D6 | |
| SCHEMBL31010991 | 0.86 | ACHE (0.39) | ALDH1A1LMNAACHETSHRALOX12 | |
| SCHEMBL9316575 | 0.84 | ALDH1A1 (0.34) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL21055985 | 0.81 | ALDH1A1 (0.34) | ALDH1A1MAPK1ACHETDP1 | |
| SCHEMBL21055984 | 0.81 | ALDH1A1 (0.34) | ALDH1A1MAPK1ACHETDP1 | |
| SCHEMBL28290020 | 0.80 | ACHE (0.36) | ALDH1A1LMNAACHETSHRALOX12 | |
| SCHEMBL6912793 | 0.77 | TDP1 (0.39) | ALDH1A1LMNACYP3A4ACHETSHR | |
| SCHEMBL18095662 | 0.77 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPK1NPC1RAB9A | |
| SCHEMBL3289166 | 0.74 | ACHE (0.48) | ALDH1A1LMNACYP3A4CYP2D6NPC1 | |
| SCHEMBL12283588 | 0.74 | ACHE (0.48) | ALDH1A1LMNACYP3A4CYP2D6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434253-B2 | Enantiopure terphenyls with two ortho-atropisomeric axes | UNIVERSITE DE STRASBOURG (FR) | 2022-09-06 | — | — | US | disclosed |
| US-20210070785-A1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-03-11 | — | — | US | disclosed |
| EP-3498684-B1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | UNIV STRASBOURG (FR) | 2020-10-14 | — | — | EP | disclosed |
| EP-3498684-A1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | Université de Strasbourg (FR) | 2019-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434253-B2 | Enantiopure terphenyls with two ortho-atropisomeric axes | THOP1, COMT, TPR | ALDH1A1 1707/4885LMNA 4825/4885MAPK1 2554/4885 |
| US-20210070785-A1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | THOP1, COMT, TPR | ALDH1A1 1707/4885LMNA 4825/4885MAPK1 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.