Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21055984 | 1.00 | ALDH1A1 (0.34) | ALDH1A1ACHETDP1MAPK1CYP1A2 | |
| SCHEMBL21055989 | 0.81 | ALDH1A1 (0.37) | ALDH1A1ACHETDP1MAPK1 | |
| SCHEMBL21055988 | 0.81 | ALDH1A1 (0.37) | ALDH1A1ACHETDP1MAPK1 | |
| SCHEMBL11759062 | 0.77 | TRPA1 (0.45) | ALDH1A1ACHETDP1 | |
| SCHEMBL2787907 | 0.76 | TDP1 (0.37) | ALDH1A1ACHETDP1CYP1A2CYP2A6 | |
| SCHEMBL235851 | 0.73 | ACHE (0.50) | ALDH1A1ACHETDP1CYP2A6 | |
| SCHEMBL4401131 | 0.73 | ACHE (0.50) | ALDH1A1ACHETDP1CYP2A6 | |
| SCHEMBL31010991 | 0.73 | ACHE (0.39) | ALDH1A1ACHETDP1CYP2A6 | |
| SCHEMBL28350315 | 0.73 | ALDH1A1 (0.62) | ALDH1A1ACHETDP1CYP1A2CYP2A6 | |
| SCHEMBL19500053 | 0.72 | ACHE (0.33) | ACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434253-B2 | Enantiopure terphenyls with two ortho-atropisomeric axes | UNIVERSITE DE STRASBOURG (FR) | 2022-09-06 | — | — | US | disclosed |
| US-20210070785-A1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-03-11 | — | — | US | disclosed |
| EP-3724154-A1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | Université de Strasbourg (FR) | 2020-10-21 | — | — | EP | disclosed |
| EP-3498684-B1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | UNIV STRASBOURG (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019115597-A1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | UNIVERSITE DE STRASBOURG (FR) | 2019-06-20 | — | — | WO | disclosed |
| EP-3498684-A1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | Université de Strasbourg (FR) | 2019-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434253-B2 | Enantiopure terphenyls with two ortho-atropisomeric axes | THOP1, COMT, TPR | ALDH1A1 1707/4885ACHE 22/4885TDP1 2414/4885 |
| US-20210070785-A1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | THOP1, COMT, TPR | ALDH1A1 1707/4885ACHE 22/4885TDP1 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.