Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251644 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2LMNATDP1TP53LTA4H | |
| SCHEMBL10801816 | 0.78 | TAAR1 (0.44) | SMN1; SMN2NOTUMLMNAHTTKMT2A | |
| SCHEMBL22100463 | 0.77 | LMNA (0.54) | SMN1; SMN2LMNATDP1TP53HTT | |
| SCHEMBL19411968 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2LMNATDP1NPC1RAB9A | |
| SCHEMBL16661732 | 0.74 | — | — | |
| SCHEMBL4671885 | 0.73 | MAPK1 (0.49) | LMNATDP1TP53LTA4HHTT | |
| SCHEMBL27894151 | 0.73 | KMT2A (0.51) | SMN1; SMN2LMNATDP1NPC1RAB9A | |
| SCHEMBL1964058 | 0.73 | ALDH1A1 (0.42) | SMN1; SMN2LMNATDP1NPC1RAB9A | |
| SCHEMBL29500180 | 0.73 | LMNA (0.72) | SMN1; SMN2LMNATDP1NPC1RAB9A | |
| SCHEMBL11884436 | 0.73 | LMNA (0.54) | SMN1; SMN2NOTUMLMNATDP1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11439147-B2 | 3-pyridyl oxyaniline compound and use of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-09-13 | — | — | US | disclosed |
| US-11439147-B2 | 3-pyridyl oxyaniline compound and use of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-09-13 | — | — | US | disclosed |
| CN-110944993-B | 3-pyridyloxyanilide compounds and use thereof | 住友化学株式会社 | 2022-07-01 | — | — | CN | disclosed |
| CN-110944993-B | 3-pyridyloxyanilide compounds and use thereof | 住友化学株式会社 | 2022-07-01 | — | — | CN | disclosed |
| CN-109563040-B | 3-pyridyloxyaniline compound and use thereof | 住友化学株式会社 | 2021-12-03 | — | — | CN | disclosed |
| CN-109563040-B | 3-pyridyloxyaniline compound and use thereof | 住友化学株式会社 | 2021-12-03 | — | — | CN | disclosed |
| US-10966427-B2 | 3-pyridyl oxyanilide compound and use therefor | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-04-06 | — | — | US | disclosed |
| US-20200120934-A1 | 3-PYRIDYL OXYANILIDE COMPOUND AND USE THEREFOR | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-04-23 | — | — | US | disclosed |
| CN-110944993-A | 3-pyridyloxyanilide compounds and use thereof | 住友化学株式会社 | 2020-03-31 | — | — | CN | disclosed |
| CN-110944993-A | 3-pyridyloxyanilide compounds and use thereof | 住友化学株式会社 | 2020-03-31 | — | — | CN | disclosed |
| US-20190183122-A1 | 3-PYRIDYL OXYANILINE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190183122-A1 | 3-PYRIDYL OXYANILINE COMPOUND AND USE OF SAME | NOTUM, WEE1, ORMDL3 | SMN1; SMN2 3020/4885NOTUM 1/4885LMNA 4000/4885 |
| US-20200120934-A1 | 3-PYRIDYL OXYANILIDE COMPOUND AND USE THEREFOR | NOTUM, WEE2, WEE1 | SMN1; SMN2 4720/4885NOTUM 1/4885LMNA 4245/4885 |
| US-10966427-B2 | 3-pyridyl oxyanilide compound and use therefor | NOTUM, WEE2, WEE1 | SMN1; SMN2 4720/4885NOTUM 1/4885LMNA 4245/4885 |
| US-11439147-B2 | 3-pyridyl oxyaniline compound and use of same | NOTUM, WEE1, ORMDL3 | SMN1; SMN2 3020/4885NOTUM 1/4885LMNA 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.