Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623079 | 0.77 | HPGD (0.50) | RAB9ACYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL14433854 | 0.77 | SCN9A (0.60) | KMT2AMEN1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL20172469 | 0.74 | KMT2A (0.62) | KMT2AMEN1RAB9ACYP11B1CYP11B2 | |
| SCHEMBL29354416 | 0.73 | CYP1A2 (0.52) | KMT2AMEN1RAB9ACYP1A2NPC1 | |
| SCHEMBL21058280 | 0.73 | SMN1; SMN2 (0.50) | KMT2ARAB9ACYP11B1CYP11B2NAMPT | |
| SCHEMBL9818933 | 0.73 | LMNA (0.44) | KMT2AMEN1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL11552476 | 0.71 | TDP1 (0.62) | KMT2ACYP11B1CYP11B2MAPTALDH1A1 | |
| SCHEMBL8940741 | 0.70 | MEN1 (0.57) | KMT2AMEN1RAB9ACYP3A4CYP2C19 | |
| SCHEMBL5797924 | 0.70 | — | — | |
| SCHEMBL10984578 | 0.69 | RAB9A (0.71) | KMT2AMEN1RAB9ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528710-B | Aminomethyl-4-imidazoles | HOFFMANN LA ROCHE | 2012-11-07 | — | — | CN | disclosed |