Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12376509 | 0.78 | HTR1D (0.55) | HTR1DMAPTHTR1BPRKAB2PRKAG1 | |
| SCHEMBL23490734 | 0.76 | HTR1D (0.42) | HTR1DMAPTHTR1BPRKAB2PRKAG1 | |
| SCHEMBL23030512 | 0.74 | HTR2A (0.46) | HTR1DMAPTHTR1BPRKAB2PRKAG1 | |
| SCHEMBL23030468 | 0.73 | HTR1D (0.43) | HTR1DMAPTHTR1BPRKAB2PRKAG1 | |
| SCHEMBL6203514 | 0.72 | SLC6A2 (0.49) | LMNAIDO1CYP2D6 | |
| SCHEMBL29055659 | 0.71 | GPR84 (0.62) | NR4A2HTR1DMEN1MAPTKMT2A | |
| SCHEMBL7220652 | 0.70 | NR4A2 (0.36) | NR4A2HTR1DMEN1MAPTKMT2A | |
| SCHEMBL20287858 | 0.70 | PRKAB2 (0.37) | NR4A2MAPTLMNAPRKAB2PRKAG1 | |
| SCHEMBL3388496 | 0.69 | GPR84 (0.59) | NR4A2MEN1KMT2ARAB9AGPR84 | |
| SCHEMBL21669262 | 0.68 | CYP3A4 (0.45) | LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308637-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308637-B2 | Therapeutic inhibitory compounds | KLKB1, SERPINB1, SERPINE1 | NR4A2 3792/4885HTR1D 2492/4885MEN1 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.