Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.55 |
| ▸ | VDR | P11473 | 8/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154939 | 0.99 | HMGCR (0.54) | HMGCRVDRCYP24A1HDAC4MEF2D | |
| SCHEMBL6155341 | 0.91 | HMGCR (0.54) | HMGCRVDRCYP24A1HDAC4MEF2D | |
| SCHEMBL2108299 | 0.90 | HMGCR (0.53) | HMGCRVDRCYP24A1HDAC4MEF2D | |
| SCHEMBL2106283 | 0.82 | HMGCR (0.57) | HMGCRAKR1B10AKR1B1 | |
| SCHEMBL2106865 | 0.82 | HMGCR (0.57) | HMGCRVDRCYP24A1HDAC4MEF2D | |
| SCHEMBL2108149 | 0.82 | HMGCR (0.57) | HMGCRAKR1B10AKR1B1 | |
| SCHEMBL2106863 | 0.82 | HMGCR (0.57) | HMGCRVDRCYP24A1HDAC4MEF2D | |
| SCHEMBL2107875 | 0.82 | HMGCR (0.57) | HMGCRVDRCYP24A1AKR1B10AKR1B1 | |
| SCHEMBL2107876 | 0.82 | HMGCR (0.57) | HMGCRVDRCYP24A1AKR1B10AKR1B1 | |
| SCHEMBL2108148 | 0.82 | HMGCR (0.57) | HMGCRAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | claimed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | claimed |
| US-11730682-B2 | Self-standing cosmetic sheet | L'OREAL (FR) | 2023-08-22 | — | — | US | disclosed |
| EP-2836187-B1 | SELF-STANDING COSMETIC SHEET | OREAL (FR) | 2021-12-08 | — | — | EP | disclosed |
| US-20180235849-A1 | SELF-STANDING COSMETIC SHEET | L'OREAL (FR) | 2018-08-23 | — | — | US | disclosed |
| US-9949897-B2 | Self-standing cosmetic sheet | L'OREAL (FR) | 2018-04-24 | — | — | US | disclosed |
| US-20150209243-A1 | SELF-STANDING COSMETIC SHEET | L'OREAL (FR) | 2015-07-30 | — | — | US | disclosed |
| EP-2836187-A1 | SELF-STANDING COSMETIC SHEET | L'Oréal (FR) | 2015-02-18 | — | — | EP | disclosed |
| EP-1658838-B1 | Emulsification system for use in cosmetics | ORÉAL L (FR) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013153678-A1 | SELF-STANDING COSMETIC SHEET | L'OREAL (FR) | 2013-10-17 | — | — | WO | disclosed |
| US-8158136-B2 | Emulsification system for use in cosmetics | L'ORÉAL (FR) | 2012-04-17 | — | — | US | disclosed |
| US-20060039936-A1 | Emulsification system for use in cosmetics | L'OREAL (FR) | 2006-02-23 | — | — | US | disclosed |
| US-20050169945-A1 | Composition for protecting keratin material, process of making, uses thereof | L'OREAL (FR) | 2005-08-04 | — | — | US | disclosed |
| EP-1559398-A1 | Process for preparing a composition for the cosmetic treatment of keratinous materials on the basis of a pressurised fluid and vitamins | L'OREAL (FR) | 2005-08-03 | — | — | EP | disclosed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | L'OREAL (FR) | 2002-12-26 | — | — | US | disclosed |
| EP-1262168-A1 | Composition containing fibres to combat the skin aging process | L'OREAL (FR) | 2002-12-04 | — | — | EP | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | CYP24A1, CYP27B1, CYP2R1 | HMGCR 283/4885VDR 4/4885CYP24A1 1/4885 |
| US-20150209243-A1 | SELF-STANDING COSMETIC SHEET | CUTA, SUCLG1, SIGLEC7 | HMGCR 691/4885VDR 4601/4885CYP24A1 3786/4885 |
| US-20180235849-A1 | SELF-STANDING COSMETIC SHEET | CUTA, DSG1, SUCLG1 | HMGCR 565/4885VDR 4085/4885CYP24A1 2442/4885 |
| US-11730682-B2 | Self-standing cosmetic sheet | CUTA, DSG1, SUCLG1 | HMGCR 565/4885VDR 4085/4885CYP24A1 2442/4885 |
| US-20050169945-A1 | Composition for protecting keratin material, process of making, uses thereof | KRT18, PROC, CUTA | HMGCR 1113/4885VDR 514/4885CYP24A1 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.