SCHEMBL2107299

SCHEMBL2107299

CO[Si](C)(C)CNC(N)=O

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2460035 0.82 TSHR (0.35) TSHRKDM4ELMNATDP1
SCHEMBL2108837 0.80 MTNR1A (0.35) TSHRPOLBTDP1
SCHEMBL728026 0.79 TSHR (0.36) TSHRKDM4ELMNATDP1
SCHEMBL2900184 0.79 TSHR (0.36) TSHR
SCHEMBL8503644 0.79 EPHX1 (0.39) TSHR
SCHEMBL432322 0.77 EPHX1 (0.34) TSHRKDM4EPOLB
SCHEMBL764270 0.75
SCHEMBL4092874 0.73 TDP1 (0.36) TSHRLMNAPOLBTDP1
SCHEMBL6066974 0.72 ALDH1A1 (0.38) TSHR
SCHEMBL5324563 0.72 TSHR (0.46) TSHRLMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1870342-B1 PAPER CONTAINER KURARAY CO (JP) 2014-05-07 EP disclosed
US-8158226-B2 Paper container KURARAY CO., LTD. (JP) 2012-04-17 US disclosed
US-20090297741-A1 PAPER CONTAINER KURARAY CO., LTD. (JP) 2009-12-03 US disclosed
EP-1870342-A1 PAPER CONTAINER KURARAY CO., LTD. (JP) 2007-12-26 EP disclosed