SCHEMBL21077348

SCHEMBL21077348

CCCOC(=O)NC(C)=O

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.43
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
HPGD P15428 1/20 0.42
EPHX1 P07099 1/20 0.42
ALDH1A1 P00352 3/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HCAR2 Q8TDS4 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2912153 0.87 ACHE (0.48) ACHEKDM4EGLAHPGDEPHX1
SCHEMBL11627977 0.86 ALDH1A1 (0.58) ACHEHPGDEPHX1ALDH1A1
SCHEMBL14902005 0.83 EPHX1 (0.66) ACHEEPHX1
SCHEMBL9842283 0.82 ACHE (0.41) ACHEKDM4EGLAHPGDEPHX1
SCHEMBL27393398 0.81 ACHE (0.43) ACHEKDM4EGLAHPGDEPHX1
SCHEMBL2105768 0.80
SCHEMBL2184403 0.79 SMN1; SMN2 (0.47) ACHEKDM4EGLAHPGDEPHX1
SCHEMBL10957874 0.79 ACHE (0.33) ACHEEPHX1MAPK1SMN1; SMN2
SCHEMBL2930085 0.79 TSHR (0.40) ACHEKDM4EGLAHPGDEPHX1
SCHEMBL28962241 0.77 EPHX1 (0.39) ACHEEPHX1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3492526-A1 RESIN COMPOSITION AND USE THEREOF Sumitomo Chemical Company Limited (JP) 2019-06-05 EP disclosed