Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765424 | 0.84 | EPHX1 (0.61) | ACHEEPHX1 | |
| SCHEMBL2912153 | 0.84 | ACHE (0.48) | ACHEKDM4EGLAHPGDEPHX1 | |
| SCHEMBL10943550 | 0.82 | — | — | |
| SCHEMBL21077348 | 0.82 | ACHE (0.43) | ACHEKDM4EGLAHPGDEPHX1 | |
| SCHEMBL11085534 | 0.78 | SMN1; SMN2 (0.39) | ACHEKDM4EGLAHPGDEPHX1 | |
| SCHEMBL27393398 | 0.77 | ACHE (0.43) | ACHEKDM4EGLAHPGDEPHX1 | |
| SCHEMBL2184403 | 0.76 | SMN1; SMN2 (0.47) | ACHEKDM4EGLAHPGDEPHX1 | |
| SCHEMBL2930085 | 0.75 | TSHR (0.40) | ACHEKDM4EGLAHPGDEPHX1 | |
| SCHEMBL6136635 | 0.74 | HPGD (0.43) | ACHEKDM4EGLAHPGDEPHX1 | |
| SCHEMBL2656053 | 0.74 | ACHE (0.48) | ACHEKDM4EGLAHPGDEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461264-A1 | ETHYNYLPHENYL DERIVATIVE, PRODUCTION THEREOF, AND REMEDY FOR DISEASES OF CIRCULATORY ORGANS CONTAINING THE SAME AS ACTIVE INGREDIENT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |