Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.31 |
| ▸ | ATM | Q13315 | 3/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19866332 | 0.93 | PRKCZ (0.34) | SMN1; SMN2PRKCZMEN1KMT2AATM | |
| SCHEMBL19866329 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2PRKCZMEN1KMT2AATM | |
| SCHEMBL19866193 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2PRKCZMEN1KMT2AATM | |
| SCHEMBL19866242 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL17047692 | 0.72 | RAB9A (0.42) | SMN1; SMN2MEN1KMT2AATMALDH1A1 | |
| SCHEMBL19866244 | 0.72 | MAOB (0.41) | SMN1; SMN2MEN1KMT2AATMALDH1A1 | |
| SCHEMBL21610400 | 0.72 | MAPT (0.43) | SMN1; SMN2PRKCZMEN1KMT2AATM | |
| SCHEMBL21078628 | 0.71 | MAOB (0.45) | SMN1; SMN2ATMALDH1A1LMNAGAA | |
| SCHEMBL11456700 | 0.68 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL19866238 | 0.67 | KMT2A (0.45) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190166840-A1 | SUBSTITUTED PYRAZOLINYL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190166840-A1 | SUBSTITUTED PYRAZOLINYL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | HPD, GMDS, WEE1 | SMN1; SMN2 4865/4885PRKCZ 3586/4885MEN1 3938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.