Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.45 |
| ▸ | MAOA | P21397 | 8/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19866226 | 0.89 | MAOB (0.46) | MAOBMAOASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL19866245 | 0.82 | ESD (0.47) | RIPK1KIF11SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL19866187 | 0.79 | MAOB (0.51) | MAOBMAOARIPK1KIF11SMN1; SMN2 | |
| SCHEMBL19866329 | 0.75 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL19866328 | 0.74 | ESD (0.49) | MAOBMAOASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL19866332 | 0.71 | PRKCZ (0.34) | RIPK1SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL21078439 | 0.71 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1LMNAGAAATM | |
| SCHEMBL17047692 | 0.70 | RAB9A (0.42) | SMN1; SMN2ALDH1A1LMNAKDM4EGAA | |
| SCHEMBL19866242 | 0.70 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17012695 | 0.68 | MAOB (0.64) | MAOBMAOARIPK1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190166840-A1 | SUBSTITUTED PYRAZOLINYL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190166840-A1 | SUBSTITUTED PYRAZOLINYL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | HPD, GMDS, WEE1 | MAOB 808/4885MAOA 1209/4885RIPK1 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.