SCHEMBL17047692

SCHEMBL17047692

CC1=C(C)C(O)N(c2ccccc2)C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.42
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
ATM Q13315 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
CCR1 P32246 1/20 0.37
GAA P10253 4/20 0.37
MAPT P10636 2/20 0.37
ABCB11 O95342 1/20 0.36
LMNA P02545 1/20 0.36
PTGS1 P23219 1/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11461211 0.83 HSP90AA1 (0.45) TP53MEN1KMT2ACCR1GAA
SCHEMBL17047756 0.79 KMT2A (0.39) RAB9AALDH1A1HSD17B10SMN1; SMN2MEN1
SCHEMBL19866244 0.77 MAOB (0.41) RAB9AALDH1A1SMN1; SMN2NPC1TSHR
SCHEMBL19866329 0.76 SMN1; SMN2 (0.35) RAB9AALDH1A1SMN1; SMN2NPC1TP53
SCHEMBL11456700 0.76 SMN1; SMN2 (0.53) RAB9AALDH1A1HSD17B10SMN1; SMN2NPC1
SCHEMBL17047652 0.75 NPC1 (0.30) RAB9ASMN1; SMN2NPC1TP53
SCHEMBL11453303 0.75 SLC6A2 (0.42) RAB9AALDH1A1NPC1TSHRMEN1
Hydrochloric Acid SCHEMBL11576053 0.75 SMN1; SMN2 (0.51) RAB9AALDH1A1HSD17B10SMN1; SMN2NPC1
SCHEMBL19866332 0.72 PRKCZ (0.34) ALDH1A1SMN1; SMN2MEN1KMT2AATM
SCHEMBL21078439 0.72 SMN1; SMN2 (0.33) ALDH1A1SMN1; SMN2MEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10918106-B2 Methods for hydraulic enhancement of crops Sound Agriculture Company (US) 2021-02-16 US disclosed
EP-3110808-B1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-08-29 EP disclosed
US-20180220650-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-08-09 US disclosed
US-20180220650-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-08-09 US disclosed
US-20180220650-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-08-09 US disclosed
EP-3331875-A1 PLANT GROWTH REGULATOR COMPOUNDS Syngenta Participations AG (CH) 2018-06-13 EP disclosed
US-9751867-B2 Plant growth regulating compounds SYNGENTA PARTICIPATIONS AG (CH) 2017-09-05 US disclosed
WO-2017025427-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2017-02-16 WO disclosed
WO-2017025427-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2017-02-16 WO disclosed
EP-3110808-A1 PLANT GROWTH REGULATING COMPOUNDS Syngenta Participations AG (CH) 2017-01-04 EP disclosed
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-12-22 US disclosed
WO-2015128321-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2015-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS GHDC, GAK, EIF4G2 RAB9A 1688/4885ALDH1A1 3192/4885HSD17B10 957/4885
US-10918106-B2 Methods for hydraulic enhancement of crops AQP1, AQP3, AQP4 RAB9A 1522/4885ALDH1A1 2821/4885HSD17B10 2657/4885
US-20180220650-A1 PLANT GROWTH REGULATOR COMPOUNDS GHITM, GHDC, SGTA RAB9A 2874/4885ALDH1A1 4213/4885HSD17B10 1781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.