Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369382 | 0.98 | CYP2D6 (0.40) | CYP2D6ALDH1A1HPGDALOX15ALOX12 | |
| Hydrochloric Acid SCHEMBL20923487 | 0.89 | SIGMAR1 (0.38) | MAOAHTR2AMAOB | |
| SCHEMBL5297631 | 0.87 | SIGMAR1 (0.39) | MAOAHTR2AMAOB | |
| Hydrochloric Acid SCHEMBL21051230 | 0.86 | CHRNA7 (0.44) | MAOA | |
| Benzylimidazole SCHEMBL1123480 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL28185788 | 0.79 | SIGMAR1 (0.38) | ALDH1A1HPGDSMN1; SMN2KMT2A | |
| Benzylimidazole SCHEMBL339106 | 0.79 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNA | |
| Benzylimidazole SCHEMBL16237306 | 0.77 | CHKA (0.46) | ALDH1A1SMN1; SMN2LMNA | |
| Benzylimidazole SCHEMBL3786784 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL2006408 | 0.76 | CYP2D6 (0.49) | CYP2D6ALDH1A1HPGDALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112086564-A | Passivating agent and passivation method thereof and method for preparing semiconductor film | 杭州纤纳光电科技有限公司 | 2020-12-15 | — | — | CN | disclosed |
| US-10723859-B2 | Lignin valorization in ionic liquids and deep eutectic solvent via catalysis and biocatalysis | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2020-07-28 | — | — | US | disclosed |
| US-20190203012-A1 | LIGNIN VALORIZATION IN IONIC LIQUIDS AND DEEP EUTECTIC SOLVENT VIA CATALYSIS AND BIOCATALYSIS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2019-07-04 | — | — | US | disclosed |
| CN-100402612-C | Ink-jet ink and recording material | CIBA SC HOLDING AG (CH) | 2008-07-16 | — | — | CN | disclosed |
| CN-100358952-C | Inkjet ink and recording material | CIBA SC HOLDING AG (CH) | 2008-01-02 | — | — | CN | disclosed |
| CN-1726263-A | Ink-jet ink and recording material | CIBA SC HOLDING AG (CH) | 2006-01-25 | — | — | CN | disclosed |
| CN-1486352-A | Ink-jet ink and recording material | �������⻯ѧƷ�ع�����˾ | 2004-03-31 | — | — | CN | disclosed |