SCHEMBL21083267

SCHEMBL21083267

CC(C)C/C=C/CCCC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 6/20 0.55
PPARD Q03181 5/20 0.55
PPARA Q07869 5/20 0.55
TOP1 P11387 3/20 0.55
CYP19A1 P11511 3/20 0.55
KMT2A Q03164 3/20 0.55
F7 P08709 3/20 0.55
F3 P13726 3/20 0.55
ALDH1A1 P00352 2/20 0.55
ADORA3 P0DMS8 2/20 0.55
PTGS1 P23219 2/20 0.55
RXRA P19793 1/20 0.55
OXER1 Q8TDS5 1/20 0.55
MAPT P10636 3/20 0.53
FABP4 P15090 3/20 0.53
BLM P54132 3/20 0.53
HSD17B10 Q99714 3/20 0.53
USP2 O75604 2/20 0.53
LMNA P02545 2/20 0.53
ALOX15 P16050 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26317135 1.00 PPARG (0.55) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL16357053 1.00 PPARG (0.55) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL2207906 0.94 PPARG (0.60) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL2207902 0.94 PPARG (0.60) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL11645936 0.92 PPARG (0.63) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL11645940 0.92 PPARG (0.63) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL25542656 0.87 ALDH1A1 (0.67) PPARGPPARDPPARACYP19A1KMT2A
SCHEMBL25542651 0.87 ALDH1A1 (0.67) PPARGPPARDPPARACYP19A1KMT2A
SCHEMBL6786331 0.87 PPARG (0.52) PPARGPPARDPPARATOP1CYP19A1
SCHEMBL6786335 0.87 PPARG (0.52) PPARGPPARDPPARATOP1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11738031-B2 Compositions and methods for preventing or treating muscle conditions THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-08-29 US disclosed
US-11738031-B2 Compositions and methods for preventing or treating muscle conditions THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-08-29 US disclosed
US-20220265677-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-08-25 US disclosed
US-20190167695-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2019-06-06 US disclosed
CN-101774939-A Trans-N-(4- hydroxyl-3-methoxybenzy)-8-methyl-5-nonenamide and preparation method thereof UNIV ZHEJIANG 2010-07-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190167695-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS PYGM, TNNC1, MYOF PPARG 127/4885PPARD 379/4885PPARA 148/4885
US-11738031-B2 Compositions and methods for preventing or treating muscle conditions PYGM, TNNC1, MYOF PPARG 127/4885PPARD 379/4885PPARA 148/4885
US-20220265677-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS PYGM, TNNC1, MYOF PPARG 127/4885PPARD 379/4885PPARA 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.