Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.60 |
| ▸ | PPARD | Q03181 | 4/20 | 0.60 |
| ▸ | PPARA | Q07869 | 4/20 | 0.60 |
| ▸ | F7 | P08709 | 4/20 | 0.60 |
| ▸ | F3 | P13726 | 4/20 | 0.60 |
| ▸ | TERT | O14746 | 3/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | FABP4 | P15090 | 2/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207906 | 1.00 | PPARG (0.60) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL11645936 | 0.98 | PPARG (0.63) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL11645940 | 0.98 | PPARG (0.63) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL16357053 | 0.94 | PPARG (0.55) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL26317135 | 0.94 | PPARG (0.55) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL21083267 | 0.94 | PPARG (0.55) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL25542656 | 0.93 | ALDH1A1 (0.67) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL25542651 | 0.93 | ALDH1A1 (0.67) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL6786331 | 0.85 | PPARG (0.52) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL6786335 | 0.85 | PPARG (0.52) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109364-B2 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA | 2006-09-19 | — | — | US | claimed |
| US-8765809-B2 | Ester derivative and use thereof | AJINOMOTO CO., INC. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20130053441-A1 | NOVEL ESTER DERIVATIVE AND USE THEREOF | AJINOMOTO CO., INC. (JP) | 2013-02-28 | — | — | US | disclosed |
| US-8212068-B2 | Ester derivative and use thereof | AJINOMOTO CO., INC. (JP) | 2012-07-03 | — | — | US | disclosed |
| US-7981460-B2 | Substituted benzyl ester derivative and use thereof | AJINOMOTO CO., INC. (JP) | 2011-07-19 | — | — | US | disclosed |
| US-7981460-B2 | Substituted benzyl ester derivative and use thereof | AJINOMOTO CO., INC. (JP) | 2011-07-19 | — | — | US | disclosed |
| US-7981460-B2 | Substituted benzyl ester derivative and use thereof | AJINOMOTO CO., INC. (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20090203774-A1 | SUBSTITUTED BENZYL ESTER DERIVATIVE AND USE THEREOF | AJINOMOTO CO., INC. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090203774-A1 | SUBSTITUTED BENZYL ESTER DERIVATIVE AND USE THEREOF | AJINOMOTO CO., INC. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090203774-A1 | SUBSTITUTED BENZYL ESTER DERIVATIVE AND USE THEREOF | AJINOMOTO CO., INC. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090170942-A1 | ESTER DERIVATIVE AND USE THEREOF | AJINOMOTO CO. INC (JP) | 2009-07-02 | — | — | US | disclosed |
| US-7109364-B2 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA | 2006-09-19 | — | — | US | disclosed |
| EP-1259470-A4 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040034242-A1 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA (US) | 2004-02-19 | — | — | US | disclosed |
| EP-1259470-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | Yang, Zhenhua (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001059067-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2001-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053441-A1 | NOVEL ESTER DERIVATIVE AND USE THEREOF | MEP1A, CES2, MEP1B | PPARG 3028/4885PPARD 2917/4885PPARA 3190/4885 |
| US-20090170942-A1 | ESTER DERIVATIVE AND USE THEREOF | MEP1A, CES2, F8 | PPARG 3257/4885PPARD 3272/4885PPARA 3435/4885 |
| US-20090203774-A1 | SUBSTITUTED BENZYL ESTER DERIVATIVE AND USE THEREOF | MEP1B, EBP, MEP1A | PPARG 1794/4885PPARD 2190/4885PPARA 2450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.