SCHEMBL10758787

SCHEMBL10758787

CC(c1ccc(O)cc1)(c1ccc(O)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.79
ESR2 Q92731 7/20 0.79
MMP3 P08254 1/20 0.65
BCL2L1 Q07817 1/20 0.65
CYP3A4 P08684 2/20 0.59
ALDH1A1 P00352 1/20 0.59
KIF11 P52732 2/20 0.50
LMNA P02545 2/20 0.50
TYR P14679 1/20 0.50
AR P10275 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
HTR6 P50406 1/20 0.50
ESRRG P62508 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12004872 0.91 ESR1 (0.70) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL10772499 0.91 ESR1 (0.70) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL26136547 0.91 ESR1 (0.70) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL23082207 0.89 ESR2 (0.63) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL27277 0.89 ESR1 (1.00) ESR1ESR2MMP3BCL2L1CYP3A4
Phenol SCHEMBL8987629 0.89 ESR1 (0.91) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL8031149 0.89 ESR1 (1.00) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL7935386 0.87 ESR1 (0.79) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL3664594 0.87 LMNA (0.70) ESR1ESR2MMP3BCL2L1CYP3A4
SCHEMBL21084882 0.87 ESR1 (0.66) ESR1ESR2MMP3BCL2L1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62289536-A None JP disclosed
JP-62122782-A None JP disclosed
US-11130724-B2 Compound, resin, composition, resist pattern formation method, and circuit pattern formation method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-09-28 US disclosed
US-20210070683-A1 COMPOUND, RESIN, COMPOSITION, RESIST PATTERN FORMATION METHOD AND CIRCUIT PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-03-11 US disclosed
US-20210070727-A1 COMPOUND, RESIN, COMPOSITION AND PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-03-11 US disclosed
US-20210070685-A1 COMPOUND, RESIN, COMPOSITION, RESIST PATTERN FORMATION METHOD AND CIRCUIT PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-03-11 US disclosed
WO-2018016640-A1 COMPOUND, RESIN, COMPOSITION, RESIST PATTERN FORMATION METHOD, AND CIRCUIT PATTERN FORMATION METHOD 三菱瓦斯化学株式会社 2018-01-25 WO disclosed
JP-S62289536-A 1-(P-BIPHENYLYL)-1,1-BIS(4'-HYDROXYPHENYL)METHANE DERIVATIVE IDEMITSU KOSAN CO LTD 1987-12-16 JP disclosed
US-4707464-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-11-17 US disclosed
JP-S62122782-A RECORDING MATERIAL FUJI PHOTO FILM CO LTD 1987-06-04 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210070683-A1 COMPOUND, RESIN, COMPOSITION, RESIST PATTERN FORMATION METHOD AND CIRCUIT PATTERN FORMATION METHOD RER1, RTN4, FEM1B ESR1 1539/4885ESR2 2068/4885MMP3 4754/4885
US-20210070727-A1 COMPOUND, RESIN, COMPOSITION AND PATTERN FORMATION METHOD RDX, RTN4, CROCC ESR1 1453/4885ESR2 1492/4885MMP3 2936/4885
US-20210070685-A1 COMPOUND, RESIN, COMPOSITION, RESIST PATTERN FORMATION METHOD AND CIRCUIT PATTERN FORMATION METHOD RER1, RTN4, FEM1B ESR1 1539/4885ESR2 2068/4885MMP3 4754/4885
US-11130724-B2 Compound, resin, composition, resist pattern formation method, and circuit pattern formation method RER1, NBAS, INTS9 ESR1 713/4885ESR2 1033/4885MMP3 4706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.