Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 5/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21118422 | 0.78 | SLC6A3 (0.41) | SLC6A3 | |
| SCHEMBL8214129 | 0.76 | CCNB2 (0.40) | — | |
| SCHEMBL28105988 | 0.73 | ADRA2C (0.45) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL4370028 | 0.71 | ADORA1 (0.41) | HTR1AADRA1ALRRK2IRAK4KDR | |
| SCHEMBL30637279 | 0.70 | HTR2A (0.42) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL28836229 | 0.70 | CCR1 (0.34) | HTR1AADRA1A | |
| SCHEMBL7832083 | 0.70 | KDM4E (0.36) | — | |
| SCHEMBL4370037 | 0.68 | NOS2 (0.41) | ZAP70 | |
| Hydrochloric Acid SCHEMBL28836198 | 0.68 | CYP1A2 (0.35) | HTR1AADRA1A | |
| SCHEMBL9052939 | 0.68 | HTR2A (0.39) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019110703-A1 | IMIDAZOPYRIDINE DERIVATIVES AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-06-13 | — | — | WO | disclosed |