Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 4/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.40 |
| ▸ | GSK3A | P49840 | 4/20 | 0.40 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.40 |
| ▸ | PDE9A | O76083 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219558 | 0.81 | CCNB2 (0.42) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL4370028 | 0.79 | ADORA1 (0.41) | CDK1GSK3AGSK3BPARP14 | |
| SCHEMBL7832083 | 0.78 | KDM4E (0.36) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL28836229 | 0.78 | CCR1 (0.34) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL8220461 | 0.77 | KDM5B (0.46) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL28836198 | 0.76 | CYP1A2 (0.35) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL4370037 | 0.76 | NOS2 (0.41) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL21087641 | 0.76 | ADRB2 (0.38) | — | |
| SCHEMBL13908156 | 0.75 | LMNA (0.60) | PDE9ALMNAKMT2ACACNA1HIDO1 | |
| SCHEMBL3950341 | 0.75 | GSK3B (0.38) | CCNB2CDK1CCNB1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002772-A1 | IMIDAZOPYRIDINE DERIVATIVES AND PBK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2011-01-06 | — | — | WO | disclosed |