Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eclanamine SCHEMBL29388487 | 1.00 | OPRK1 (0.41) | OPRK1SIGMAR1CYP3A4CYP2D6TSHR | |
| Eclanamine SCHEMBL11446626 | 1.00 | OPRK1 (0.41) | OPRK1SIGMAR1CYP3A4CYP2D6TSHR | |
| Eclanamine SCHEMBL29368460 | 0.93 | SLC6A4 (0.40) | OPRK1SIGMAR1CYP3A4CYP2D6TSHR | |
| Eclanamine SCHEMBL124915 | 0.93 | SLC6A4 (0.40) | OPRK1SIGMAR1CYP3A4CYP2D6TSHR | |
| SCHEMBL11443857 | 0.87 | TACR1 (0.41) | OPRK1SIGMAR1CYP3A4CYP2D6TSHR | |
| SCHEMBL11443856 | 0.87 | TACR1 (0.41) | OPRK1SIGMAR1CYP3A4CYP2D6TSHR | |
| SCHEMBL11447020 | 0.87 | OPRD1 (0.42) | OPRK1SIGMAR1OPRM1ALDH1A1OPRD1 | |
| SCHEMBL11498170 | 0.86 | TACR1 (0.44) | OPRK1SIGMAR1CYP3A4CYP2D6TSHR | |
| SCHEMBL11378463 | 0.83 | TACR1 (0.44) | OPRK1SIGMAR1CYP3A4CYP2D6TSHR | |
| SCHEMBL11571115 | 0.83 | TACR1 (0.45) | OPRK1SIGMAR1CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228488-A1 | EXTENDED RELEASE COMPOSITIONS AND PROCESS FOR PREPARATION | RUBICON RES PRIVATE LIMITED (IN) | 2021-07-29 | — | — | US | claimed |
| US-20190262268-A1 | ORAL MODIFIED RELEASE FORMULATIONS | RUBICON RES PRIVATE LIMITED (IN) | 2019-08-29 | — | — | US | claimed |
| WO-2018055641-A1 | ORAL MODIFIED RELEASE FORMULATIONS | RUBICON RESEARCH PRIVATE LIMITED (IN) | 2018-03-29 | — | — | WO | claimed |
| US-20170128379-A1 | MODIFIED RELEASE PHARMACEUTICAL PREPARATIONS | RUBICON RESEARCH PRIVATE LIMITED (IN) | 2017-05-11 | — | — | US | claimed |
| WO-2016001937-A2 | MODIFIED RELEASE PHARMACEUTICAL PREPARATIONS | RUBICON RESEARCH PRIVATE LIMITED (IN) | 2016-01-07 | — | — | WO | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| WO-1997041878-A1 | TREATMENT OF MOOD DISORDERS WITH A GROWTH HORMONE SECRETAGOGUE | MERCK & CO., INC. (US) | 1997-11-13 | — | — | WO | claimed |
| WO-2024107708-A1 | TAAR RECEPTOR AGONISTS FOR SEXUAL DYSFUNCTION | ReJoy (US) | 2024-05-23 | — | — | WO | disclosed |
| US-11383084-B2 | Treatment of dermatological conditions via neuromodulation | PALO ALTO INVESTORS (US) | 2022-07-12 | — | — | US | disclosed |
| US-11337937-B2 | TARR receptor agonists for sexual dysfunction | JOHN MCCOY | 2022-05-24 | — | — | US | disclosed |
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| US-4157398-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4156733-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4156015-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |
| US-4148913-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | disclosed |