Eclanamine

Eclanamine

SCHEMBL29388487

CCC(=O)N(c1ccc(Cl)c(Cl)c1)[C@@H]1CCC[C@@H]1N(C)C

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 6/20 0.41
▸ SIGMAR1 Q99720 6/20 0.41
▸ CYP3A4 P08684 3/20 0.41
▸ CYP2D6 P10635 3/20 0.41
▸ TSHR P16473 3/20 0.41
▸ OPRM1 P35372 2/20 0.41
▸ TP53 P04637 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ OPRD1 P41143 2/20 0.41
▸ CYP1A2 P05177 2/20 0.41
▸ CYP2C19 P33261 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ MTOR P42345 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ MAPK8 P45983 1/20 0.41
▸ MAPK9 P45984 1/20 0.41
▸ MAPK10 P53779 1/20 0.41
▸ TACR1 P25103 3/20 0.41
▸ SLC6A4 P31645 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eclanamine SCHEMBL2109152 1.00 OPRK1 (0.41) OPRK1SIGMAR1CYP3A4CYP2D6TSHR
Eclanamine SCHEMBL11446626 1.00 OPRK1 (0.41) OPRK1SIGMAR1CYP3A4CYP2D6TSHR
Eclanamine SCHEMBL29368460 0.93 SLC6A4 (0.40) OPRK1SIGMAR1CYP3A4CYP2D6TSHR
Eclanamine SCHEMBL124915 0.93 SLC6A4 (0.40) OPRK1SIGMAR1CYP3A4CYP2D6TSHR
SCHEMBL11443857 0.87 TACR1 (0.41) OPRK1SIGMAR1CYP3A4CYP2D6TSHR
SCHEMBL11443856 0.87 TACR1 (0.41) OPRK1SIGMAR1CYP3A4CYP2D6TSHR
SCHEMBL11447020 0.87 OPRD1 (0.42) OPRK1SIGMAR1OPRM1ALDH1A1OPRD1
SCHEMBL11498170 0.86 TACR1 (0.44) OPRK1SIGMAR1CYP3A4CYP2D6TSHR
SCHEMBL11378463 0.83 TACR1 (0.44) OPRK1SIGMAR1CYP3A4CYP2D6TSHR
SCHEMBL11571115 0.83 TACR1 (0.45) OPRK1SIGMAR1CYP3A4CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116239715-B Application of DCDPP-2TPA as PET-RAFT controllable active polymerization photocatalyst 中国科学院深圳先进技术研究院 2024-04-02 — — CN claimed
CN-116239715-A Application of DCDPP-2TPA as PET-RAFT controllable active polymerization photocatalyst 中国科学院深圳先进技术研究院 2023-06-09 — — CN claimed
CN-119390976-A Preparation of heterogeneous photocatalyst and application of heterogeneous photocatalyst in controllable free radical polymerization 河北大学 2025-02-07 — — CN disclosed
US-12162889-B2 Luminogens for biological applications THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-12-10 — — US disclosed
US-12162889-B2 Luminogens for biological applications THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-12-10 — — US disclosed
CN-116239715-B Application of DCDPP-2TPA as PET-RAFT controllable active polymerization photocatalyst 中国科学院深圳先进技术研究院 2024-04-02 — — CN disclosed
CN-116239715-B Application of DCDPP-2TPA as PET-RAFT controllable active polymerization photocatalyst 中国科学院深圳先进技术研究院 2024-04-02 — — CN disclosed
CN-116239715-B Application of DCDPP-2TPA as PET-RAFT controllable active polymerization photocatalyst 中国科学院深圳先进技术研究院 2024-04-02 — — CN disclosed
CN-110312708-B Luminescent materials for biological applications 香港科技大学 2023-07-18 — — CN disclosed
CN-110312708-B Luminescent materials for biological applications 香港科技大学 2023-07-18 — — CN disclosed
CN-116239715-A Application of DCDPP-2TPA as PET-RAFT controllable active polymerization photocatalyst 中国科学院深圳先进技术研究院 2023-06-09 — — CN disclosed
CN-116239715-A Application of DCDPP-2TPA as PET-RAFT controllable active polymerization photocatalyst 中国科学院深圳先进技术研究院 2023-06-09 — — CN disclosed
CN-116239715-A Application of DCDPP-2TPA as PET-RAFT controllable active polymerization photocatalyst 中国科学院深圳先进技术研究院 2023-06-09 — — CN disclosed
US-20220048923-A1 LUMINOGENS FOR BIOLOGICAL APPLICATIONS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2022-02-17 — — US disclosed
US-20220048923-A1 LUMINOGENS FOR BIOLOGICAL APPLICATIONS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2022-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162889-B2 Luminogens for biological applications BTD, TPD52L2, TTPA OPRK1 3646/4885SIGMAR1 2797/4885CYP3A4 2973/4885
US-20220048923-A1 LUMINOGENS FOR BIOLOGICAL APPLICATIONS BTD, TPD52L2, TTPA OPRK1 3646/4885SIGMAR1 2797/4885CYP3A4 2973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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