Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21092244 | 0.87 | ESR1 (0.46) | MEN1KMT2ACYP1A2PPARDALDH1A1 | |
| SCHEMBL11726825 | 0.79 | CYP19A1 (0.38) | PPARGPPARD | |
| SCHEMBL11750596 | 0.78 | CYP1A2 (0.48) | ALOX15CYP1A2PPARGALDH1A1PPARA | |
| SCHEMBL11749703 | 0.78 | MAPK1 (0.63) | PTPN7MEN1KMT2ACYP1A2PPARG | |
| SCHEMBL29543994 | 0.78 | OPRD1 (0.43) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL2485975 | 0.78 | OPRD1 (0.43) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL11746234 | 0.77 | KDM4E (0.46) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL11752639 | 0.77 | HTR1A (0.33) | — | |
| SCHEMBL20856119 | 0.77 | CYP19A1 (0.51) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL11724770 | 0.76 | LMNA (0.39) | ALOX15ALDH1A1MAPTESR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817299-B1 | SUBSTITUTED CHROMAN COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LTD (IN) | 2019-06-12 | — | — | EP | disclosed |