Iodide

Iodide

SCHEMBL663030

I.c1ccc(C2COC(CN3CCCCC3)(c3ccccc3)O2)cc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 10/20 0.38
ADRA1D P25100 10/20 0.38
ADRA1A P35348 10/20 0.38
ADRA1B P35368 10/20 0.38
LTA4H P09960 4/20 0.36
HRH1 P35367 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2109364 0.99 HTR1A (0.39) HTR1AADRA1DADRA1AADRA1BLTA4H
SCHEMBL9458455 0.76 TSHR (0.41)
SCHEMBL751259 0.76 TSHR (0.41)
SCHEMBL11451929 0.69 TSHR (0.37)
SCHEMBL11452742 0.68 ADRA1A (0.47) ADRA1A
SCHEMBL16973469 0.64 TSHR (0.45)
SCHEMBL10759760 0.64 TMEM97 (0.49) HTR1AADRA1DADRA1AADRA1B
SCHEMBL25197896 0.64 SIGMAR1 (0.64) HTR1AADRA1DADRA1AADRA1BLTA4H
Hydrochloric Acid SCHEMBL30904664 0.63 HTR1A (0.67) HTR1AADRA1DADRA1AADRA1B
SCHEMBL16507131 0.62 SLC6A4 (0.55) HRH1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed
EP-4692178-A1 CELLULOSE POWDER AND MOLDED BODY Asahi Kasei Kabushiki Kaisha (JP) 2026-02-11 EP disclosed
US-12427113-B2 Cellulose composition, tablet, and orally disintegrating tablet ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-30 US disclosed
WO-2025105451-A1 SOLID PREPARATION 第一三共ヘルスケア株式会社 2025-05-22 WO disclosed
WO-2025100523-A1 METHOD FOR PRODUCING SOLID PREPARATION, AND TABLETS 第一三共ヘルスケア株式会社 2025-05-15 WO disclosed
WO-2025100462-A1 SOLID COMPOSITION CONTAINING BROMHEXINE 第一三共ヘルスケア株式会社 2025-05-15 WO disclosed
US-12290602-B2 Cellulose powder, use thereof, and tablets ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-05-06 US disclosed
EP-4056637-B1 CELLULOSE COMPOSITION AND TABLET ASAHI CHEMICAL IND (JP) 2025-02-12 EP disclosed
CN-112585192-B Cellulose powder, use thereof and tablets 旭化成株式会社 2023-11-21 CN disclosed
US-20230055674-A1 CELLULOSE COMPOSITION AND TABLET ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-02-23 US disclosed
CN-101203553-A Porous cellulose aggregate and molding composition thereof ASAHI CHEMICAL CORP (JP) 2008-06-18 CN disclosed
US-7335776-B2 Remedies for depression containing EP1 antagonist as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-02-26 US disclosed
EP-1873196-A1 POROUS CELLULOSE AGGREGATE AND MOLDING COMPOSITION THEREOF Asahi Kasei Chemicals Corporation (JP) 2008-01-02 EP disclosed
US-20070190017-A1 Porous cellulose aggregate and formed product composition comprising the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2007-08-16 US disclosed
EP-1712583-A1 POROUS CELLULOSE AGGREGATE AND FORMED PRODUCT COMPOSITION COMPRISING THE SAME Asahi Kasei Chemicals Corporation (JP) 2006-10-18 EP disclosed
US-20040082653-A1 Remedies for depression containing ep1 antagonist as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1369129-A1 REMEDIES FOR DEPRESSION CONTAINING EP1 ANTAGONIST AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2003-12-10 EP disclosed
EP-0665009-B1 CRYSTALLINE CONDITION DISLOCATING METHOD NIPPON SHINYAKU CO LTD (JP) 2000-02-16 EP disclosed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US disclosed
EP-0665009-A1 CRYSTALLINE CONDITION DISLOCATING METHOD NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-08-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082653-A1 Remedies for depression containing ep1 antagonist as the active ingredient PTGER1, PTGER2, PTGS1 HTR1A 13/4885ADRA1D 169/4885ADRA1A 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.