Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21094390 | 0.89 | ALDH1A1 (0.38) | BRD4KCNH2SCN3AALDH1A1TDP1 | |
| SCHEMBL21094399 | 0.88 | KCNH2 (0.38) | KCNH2SCN3AALDH1A1TDP1RIPK1 | |
| SCHEMBL21094391 | 0.84 | KCNH2 (0.42) | KCNH2SCN3AALDH1A1TDP1RIPK1 | |
| SCHEMBL21094097 | 0.83 | ACKR3 (0.37) | KCNH2SCN3AALDH1A1TDP1MEN1 | |
| SCHEMBL21094396 | 0.82 | RIPK1 (0.39) | KCNH2SCN3AALDH1A1TDP1RIPK1 | |
| SCHEMBL21094403 | 0.81 | ALDH1A1 (0.45) | KCNH2SCN3AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL21094385 | 0.77 | PKM (0.47) | KCNH2SCN3AALDH1A1RAB9AMEN1 | |
| SCHEMBL21093660 | 0.76 | SLC6A3 (0.40) | EPHX2ALDH1A1NPC1RAB9ARIPK1 | |
| SCHEMBL20843428 | 0.73 | RIPK1 (0.41) | KCNH2SCN3AGRM5TDP1RIPK1 | |
| SCHEMBL22451655 | 0.73 | RIPK1 (0.41) | KCNH2SCN3AGRM5TDP1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019112024-A1 | PYRROLIDINE COMPOUND | キッセイ薬品工業株式会社 | 2019-06-13 | — | — | WO | disclosed |