Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14714633 | 0.77 | PLK1 (0.40) | TPMTTRPV1PLK1MAPTHPGD | |
| SCHEMBL8920815 | 0.72 | LMNA (0.50) | TPMTTRPV1MAPTHDAC1 | |
| SCHEMBL14724481 | 0.68 | MAPK1 (0.41) | MAPTGAA | |
| SCHEMBL10938164 | 0.68 | TRPV1 (0.33) | TAS1R3TAS1R1TRPV1MAPT | |
| SCHEMBL10938163 | 0.68 | TRPV1 (0.33) | TAS1R3TAS1R1TRPV1MAPT | |
| SCHEMBL470103 | 0.68 | CNR1 (0.47) | TPMTTRPV1MAPTALDH1A1TDP1 | |
| SCHEMBL7807968 | 0.67 | POLB (0.45) | TAS1R3TAS1R1MAPTKDM4EALDH1A1 | |
| SCHEMBL2144483 | 0.66 | HDAC8 (0.64) | TPMTTRPV1PLK1HPGD | |
| SCHEMBL27745010 | 0.66 | POLB (0.47) | TPMTTRPV1HDAC1 | |
| SCHEMBL7671511 | 0.66 | CXCR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562155-B1 | HYDROXAMIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2019-06-05 | — | — | EP | disclosed |