Tifenazoxide

Tifenazoxide

SCHEMBL2109690

CC1(NC2=NS(=O)(=O)c3sc(Cl)cc3N2)CC1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCC8 Q09428 12/20 0.45
KCNJ11 Q14654 12/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4410206 0.95 ABCC8 (0.47) ABCC8KCNJ11
SCHEMBL4410466 0.95 ABCC8 (0.44) ABCC8KCNJ11
SCHEMBL4563273 0.94 ABCC8 (0.44) ABCC8KCNJ11
SCHEMBL7078790 0.84 ABCC8 (0.44) ABCC8KCNJ11
SCHEMBL2344068 0.82 ABCC8 (0.45) ABCC8KCNJ11
SCHEMBL6997485 0.81 ABCC8 (0.42) ABCC8KCNJ11
SCHEMBL4411989 0.81 ABCC8 (0.38) ABCC8KCNJ11
SCHEMBL6802837 0.80 ABCC8 (0.43) ABCC8KCNJ11
SCHEMBL4268367 0.79 ABCC8 (0.37) ABCC8KCNJ11
SCHEMBL7082470 0.78 ABCC8 (0.38) ABCC8KCNJ11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340879-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACID TRANSFER CHILDRENS HOSPITAL MED CT (US) 2025-11-06 US claimed
US-12378550-B2 Compositions and methods for nucleic acid transfer CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2025-08-05 US claimed
US-10894960-B2 Compositions and methods for nucleic acid transfer CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2021-01-19 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
CN-101043891-A Therapeutic agents targeting the nc ca-atp channel and methods of use thereof UNIV MARYLAND (US) 2007-09-26 CN claimed
EP-1802313-A2 THERAPEUTIC AGENTS TRAGETING THE NCCA-ATP CHANNEL AND METHODS OF USE THEREOF University of Maryland, Baltimore (US) 2007-07-04 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20030109519-A1 Use of selective potassium channel openers NOVO NORDISK (DK) 2003-06-12 US claimed
EP-1140945-B1 FUSED 1,2,4-THIADIAZINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK AS (DK) 2003-06-04 EP claimed
US-20020193368-A1 Use of potassium channel openers for the treatment of insulitis HANSEN JOHN BONDO (DK) 2002-12-19 US claimed
US-20020086861-A1 Fused 1,2,4- thiadiazine derivatives, their preparation and use HANSEN JOHN BONDO (DK) 2002-07-04 US claimed
US-20020035106-A1 Use of potassium channel agonists for reducing fat food consumption NOVO NORDISK A/S (DK) 2002-03-21 US claimed
US-20020032193-A1 Use of potassium channel openers for the treatment of insulitis NOVO NORDISK A/S (DK) 2002-03-14 US claimed
US-20020028808-A1 Use of potassium channel agonists for the treatment of cancer NOVO NORDISK A/S (DK) 2002-03-07 US claimed
CN-1330655-A Fused 1,2,4-thiadiazine derivatives, their preparation and use NOVO NORDISK AS (DK) 2002-01-09 CN claimed
WO-2002000665-A1 USE OF POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF INSULITIS NOVO NORDISK A/S (DK) 2002-01-03 WO claimed
US-6329367-B1 NERVOUS SYSTEM DISORDERS AND CARDIOVASCULAR DISORDERS NOVO NORDISK A/S (DK) 2001-12-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340879-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACID TRANSFER SNRPE, RNASE1, POLRMT ABCC8 969/4885KCNJ11 3985/4885
US-20030109519-A1 Use of selective potassium channel openers KCNJ11, KCNJ2, KCNJ1 ABCC8 63/4885KCNJ11 1/4885
US-10894960-B2 Compositions and methods for nucleic acid transfer SNRPE, RNASE1, POLRMT ABCC8 969/4885KCNJ11 3985/4885
US-20020086861-A1 Fused 1,2,4- thiadiazine derivatives, their preparation and use CYP4F3, TBXAS1, NR3C2 ABCC8 3610/4885KCNJ11 801/4885
US-12378550-B2 Compositions and methods for nucleic acid transfer SNRPE, RNASE1, POLRMT ABCC8 969/4885KCNJ11 3985/4885
US-20020028808-A1 Use of potassium channel agonists for the treatment of cancer KCNN3, KCNN1, KCNN2 ABCC8 944/4885KCNJ11 7/4885
US-20020035106-A1 Use of potassium channel agonists for reducing fat food consumption KCNN3, KCNN2, KCNN1 ABCC8 985/4885KCNJ11 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.