Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.68 |
| ▸ | TNKS | O95271 | 6/20 | 0.48 |
| ▸ | PARP1 | P09874 | 5/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.48 |
| ▸ | WNT3A | P56704 | 3/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.48 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411302 | 0.75 | TNKS2 (0.56) | TNKS2TNKSPARP1PARP2WNT3A | |
| SCHEMBL15315468 | 0.75 | TNKS2 (0.56) | TNKS2TNKSPARP1PARP2WNT3A | |
| SCHEMBL11186819 | 0.74 | TRPV1 (0.46) | TNKS2TRPV3HRH4 | |
| Hydrochloric Acid SCHEMBL30613776 | 0.72 | HTR2C (0.67) | TNKS2TNKSPARP1WNT3AHTR2C | |
| SCHEMBL11190992 | 0.71 | MAPT (0.39) | TNKS2TRPV3 | |
| SCHEMBL11192162 | 0.69 | TRPV3 (0.37) | TRPV3 | |
| SCHEMBL30613768 | 0.69 | MAPK1 (0.45) | CDK2HTR2C | |
| SCHEMBL30613811 | 0.69 | NAAA (0.36) | TNKS2HTR2CTRPV3S1PR1HRH4 | |
| SCHEMBL11179410 | 0.68 | DRD2 (0.36) | TRPV3 | |
| SCHEMBL11187581 | 0.67 | GAA (0.37) | TRPV3S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498824-A1 | CORTICAL INTERNEURONS AND OTHER NEURONAL CELLS PRODUCED BY THE DIRECTED DIFFERENTIATION OF PLURIPOTENT AND MULTIPOTENT CELLS | Memorial Sloan-Kettering Cancer Center (US) | 2019-06-19 | — | — | EP | disclosed |