Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633231 | 0.81 | UHRF1 (0.43) | ACHECCR1CCR5CCR8 | |
| SCHEMBL19992429 | 0.79 | LOX (0.44) | NOS3NOS1NOS2ACHECCR1 | |
| SCHEMBL681637 | 0.75 | PTGS1 (0.43) | — | |
| SCHEMBL23727271 | 0.75 | LOXL2 (0.41) | — | |
| SCHEMBL27045873 | 0.75 | KDM5A (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL28969184 | 0.72 | CYP3A4 (0.30) | — | |
| SCHEMBL25299834 | 0.72 | ADRB2 (0.35) | NOS3NOS1NOS2NFKB1BLM | |
| SCHEMBL23029937 | 0.72 | CYP17A1 (0.33) | — | |
| SCHEMBL29002085 | 0.72 | MT-CO2 (0.48) | — | |
| SCHEMBL11334424 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073475-A1 | CEREBLON LIGANDS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |