Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 14/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 14/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 14/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.30 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29306465 | 0.86 | RXRA (0.33) | KDM5AKDM5BRXRAGRIN1GRIN2B | |
| SCHEMBL18458866 | 0.82 | KDM5A (0.31) | KDM5AKDM5B | |
| SCHEMBL11994362 | 0.81 | RXRA (0.40) | RXRAGRIN1GRIN2BNOS3NOS1 | |
| SCHEMBL21098120 | 0.75 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL19633231 | 0.75 | UHRF1 (0.43) | — | |
| SCHEMBL19992429 | 0.74 | LOX (0.44) | NOS3NOS1NOS2 | |
| SCHEMBL28056162 | 0.72 | MAOA (0.44) | KDM5AKDM5BNOS3NOS1NOS2 | |
| SCHEMBL827951 | 0.71 | SYK (0.48) | RXRAGRIN1GRIN2BNOS3NOS1 | |
| SCHEMBL12409018 | 0.70 | SIRT2 (0.43) | NOS3NOS1NOS2 | |
| SCHEMBL23727271 | 0.70 | LOXL2 (0.41) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025862-A1 | SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025862-A1 | SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | PFAS, DDT, NOTUM | KDM5A 250/4885KDM5B 377/4885RXRA 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.