Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292310 | 0.91 | CES2 (0.47) | CES2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10631861 | 0.89 | ALDH1A1 (0.44) | CES2ALDH1A1MAPTALOX15TSHR | |
| SCHEMBL8073087 | 0.81 | KEAP1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL10780202 | 0.80 | SLC25A5 (0.50) | — | |
| SCHEMBL8076275 | 0.80 | CYP19A1 (0.46) | MEN1USP2ALDH1A1HPNCYP3A4 | |
| SCHEMBL8076262 | 0.79 | ACHE (0.46) | TDP1 | |
| SCHEMBL8427797 | 0.78 | HDAC4 (0.39) | — | |
| SCHEMBL8427798 | 0.78 | HDAC4 (0.39) | — | |
| SCHEMBL10630399 | 0.78 | ALDH1A1 (0.47) | MEN1USP2ALDH1A1HPNCYP3A4 | |
| SCHEMBL8063137 | 0.77 | ACHE (0.51) | ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| EP-0017420-B1 | NEW DIHYDROXY-ACYLANTHRONES HAVING ANTI-PSORIATIC ACTIVITY, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THEIR USE AS ANTI-PSORIATIC AGENTS | ORION-YHTYMÄ OY (FI) | 1982-07-21 | — | — | EP | claimed |
| EP-0017420-A1 | New dihydroxy-acylanthrones having anti-psoriatic activity, process for preparing them, pharmaceutical compositions comprising them, and their use as anti-psoriatic agents | ORION-YHTYMÄ OY (FI) | 1980-10-15 | — | — | EP | claimed |
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| US-11191719-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2021-12-07 | — | — | US | disclosed |
| US-10463611-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2019-11-05 | — | — | US | disclosed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-20140154313-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2014-06-05 | — | — | US | disclosed |
| WO-1995003266-A1 | 10-SUBSTITUTED 1,8-DIHYDROXY-9(10H) ANTHRACENONE PHARMACEUTICALS | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1995-02-02 | — | — | WO | disclosed |
| WO-1994006748-A1 | NEW ANTHRONE AND ANTHRACENE DERIVATIVES SUBSTITUTED IN POSITION 10, PROCESS FOR THEIR PRODUCTION, PHARMACEUTICALS OR COSMETICS CONTAINING SAID COMPOUNDS, AND THEIR USE | BEIERSDORF AG (DE) | 1994-03-31 | — | — | WO | disclosed |
| US-4696941-A | SKIN DISORDERS, ANTIINFLAMMATORY AGENTS | Groupement d'Interet Economique dit: Centre International 'de Recherches Dermatologiques C.I.R.D. (FR) | 1987-09-29 | — | — | US | disclosed |
| EP-0017420-B1 | NEW DIHYDROXY-ACYLANTHRONES HAVING ANTI-PSORIATIC ACTIVITY, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THEIR USE AS ANTI-PSORIATIC AGENTS | ORION-YHTYMÄ OY (FI) | 1982-07-21 | — | — | EP | disclosed |
| US-4299846-A | Dihydroxy-acylanthrones having anti-psoriatic activity | ORION-YHTYMA OY (FI) | 1981-11-10 | — | — | US | disclosed |
| EP-0017420-A1 | New dihydroxy-acylanthrones having anti-psoriatic activity, process for preparing them, pharmaceutical compositions comprising them, and their use as anti-psoriatic agents | ORION-YHTYMÄ OY (FI) | 1980-10-15 | — | — | EP | disclosed |