Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1972884 | 0.82 | CA2 (0.48) | METPOLBLMNAGAAALDH1A1 | |
| SCHEMBL5739617 | 0.79 | CYP4F2 (0.51) | METPOLBLMNAGAASMN1; SMN2 | |
| SCHEMBL20751417 | 0.77 | PKM (0.47) | METLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL1196047 | 0.76 | KMT2A (0.51) | POLBLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8403545 | 0.75 | POLB (0.61) | POLBLMNAGAAALDH1A1KMT2A | |
| SCHEMBL5291483 | 0.74 | SLC7A5 (0.56) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1160586 | 0.74 | — | — | |
| SCHEMBL12844536 | 0.71 | GPR84 (0.42) | LMNAALDH1A1MEN1KMT2ATRPV6 | |
| SCHEMBL8225225 | 0.71 | — | — | |
| SCHEMBL7657773 | 0.71 | ALDH2 (0.40) | POLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019111225-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF NON‑ALCOHOLIC STEATOHEPATITIS | AVALIV THERAPEUTICS (US) | 2019-06-13 | — | — | WO | disclosed |