Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21102410 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPK1PTGDR2PDK2MAPT | |
| SCHEMBL21102406 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPK1PTGDR2PDK2MAPT | |
| SCHEMBL21102261 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPK1PTGDR2PDK2MAPT | |
| SCHEMBL21102393 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPK1PTGDR2PDK2MAPT | |
| SCHEMBL21102394 | 0.81 | MAPK1 (0.41) | ALDH1A1MAPK1CRHBPCRHR2PTGDR2 | |
| SCHEMBL14178382 | 0.81 | PTGDR2 (0.35) | ALDH1A1MAPK1PTGDR2MCL1PDK2 | |
| SCHEMBL16585739 | 0.78 | PTGDR2 (0.43) | ALDH1A1MAPK1PTGDR2MAPTKDM4E | |
| SCHEMBL26965743 | 0.78 | PTGDR2 (0.41) | ALDH1A1MAPK1PTGDR2LMNAPTPRC | |
| SCHEMBL18311777 | 0.75 | CYP2A6 (0.43) | ALDH1A1MAPK1PTGDR2MAPTKDM4E | |
| SCHEMBL21102402 | 0.75 | ALOX5 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200308129-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-10-01 | — | — | US | disclosed |
| WO-2019115577-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308129-A1 | SUBSTITUTED AROMATIC AMINES FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICES | DDC, CHRM5, AFF2 | ALDH1A1 1738/4885MAPK1 3334/4885CRHBP 4637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.